Evidence map›Paper›PMID 37408789›Full record

ArticleAging brain2023

Regional serotonin terminal density in aging human brain: A [

Prabesh Kanel, Robert A Koeppe, Vikas Kotagal, Stiven Roytman, Martijn L T M Muller, Nicolaas I Bohnen, Roger L Albin

Open access · goldAbstract read
In one paragraph

Article in Aging brain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Prabesh KanelUniversity of Michigan Morris K. Udall Center for Excellence in Parkinson's Disease Research, Ann Arbor, MI 48109, United States.
Robert A KoeppeUniversity of Michigan Morris K. Udall Center for Excellence in Parkinson's Disease Research, Ann Arbor, MI 48109, United States.
Vikas KotagalNeurology Service and GRECC, VAAAHS, Ann Arbor, MI 48105, United States.
Stiven RoytmanUniversity of Michigan Morris K. Udall Center for Excellence in Parkinson's Disease Research, Ann Arbor, MI 48109, United States.
Martijn L T M MullerUniversity of Michigan Morris K. Udall Center for Excellence in Parkinson's Disease Research, Ann Arbor, MI 48109, United States.
Nicolaas I BohnenNeurology Service and GRECC, VAAAHS, Ann Arbor, MI 48105, United States.
Roger L AlbinNeurology Service and GRECC, VAAAHS, Ann Arbor, MI 48105, United States.
University of Michigan · US

Funding

Udall Catalyst Research Project: Retrosplenial Cholinergic and Attentional-Motor Integration DysfunctionP50NS123067 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI AHMED, OMAR JAMIL · 2021 to 2025
$11.6M
CSRD VA IK2 CX001186NINDS NIH HHS P50 NS123067
6 · The paper itself

Abstract

There are conflicting results regarding regional age-related changes in serotonin terminal density in human brain. Some imaging studies suggest age-related declines in serotoninergic terminals and perikarya. Other human imaging studies and post-mortem biochemical studies suggest stable brain regional serotoninergic terminal densities across the adult lifespan. In this cross-sectional study, we used [

Indexed as

RapheSerotoninSerotonin transporter

Identifiers

PMID37408789
PMCPMC10318302
OpenAlexW4322727194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.