ArticleAdvances in radiation oncology
Early Experience of Online Adaptive Radiation Therapy for Definitive Radiation of Patients With Head and Neck Cancer.
Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Impact of daily adaptive head and neck radiotherapy on toxicity and quality of life: results of the DARTBOARD phase II randomized trial.Journal of the National Cancer Institute · 2025Trial
- Predicting the benefit of adaptive radiotherapy in head and neck Cancer using cone-beam computed tomography.Physics and imaging in radiation oncology · 2026Article
- Development of CBCT-Guided Online Adaptive Radiotherapy.Cancers · 2026Review
- Intrafractional Motion and Margin Assessment for Cone Beam Computed Tomography Guided Online Adaptive Radiation Therapy in Head and Neck Cancer.Advances in radiation oncology · 2026Article
- Solution for the hot spots in adaptive radiotherapy planning for cervical cancer: a case report and review of literature.Frontiers in oncology · 2026Article
- Adaptive radiotherapy dose prediction on head and neck cancer patients with a 3D multi-headed U-Net deep learning architecture.Machine Learning. Health · 2025Article
- Adapting to the Future: Introducing the Radiation Oncology Alliance Adaptive Radiotherapy Working Group.Journal of medical imaging and radiation oncology · 2025Article
- Online CBCT-based adaptive radiation with reduced PTV margins for prostate cancer: Does reference plan comparison tell the whole story?Clinical and translational radiation oncology · 2025Article
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- Evaluating the Impact of Invasive Intubation on Treatment Accuracy in Head and Neck Cancer Patients Undergoing Image-Guided Radiation Therapy.Advances in radiation oncology · 2025Article
- The InterVision Framework: An Enhanced Fine-Tuning Deep Learning Strategy for Auto-Segmentation in Head and Neck.Journal of personalized medicine · 2024Article
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- Adaptive radiotherapy for head and neck cancer: Pitfalls and possibilities from the radiation oncologist's point of view.Cancer medicine · 2024Review
- Real world clinical experience using daily intelligence-assisted online adaptive radiotherapy for head and neck cancer.Radiation oncology (London, England) · 2024Article
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- Physicists should perform reference planning for CBCT guided online adaptive radiotherapy.Journal of applied clinical medical physics · 2023Article
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Authors and funding
8 authors.
Funding
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Abstract
Purpose: The advent of cone beam computed tomography-based online adaptive radiation therapy (oART) has dramatically reduced the barriers of adaptation. We present the first prospective oART experience data in radiation of head and neck cancers (HNC). Methods and Materials: Patients with HNC receiving definitive standard fractionation (chemo)radiation who underwent at least 1 oART session were enrolled in a prospective registry study. The frequency of adaptations was at the discretion of the treating physician. Physicians were given the option of delivering 1 of 2 plans during adaptation: the original radiation plan transposed onto the cone beam computed tomography with adapted contours (scheduled), and a new adapted plan generated from the updated contours (adapted). A paired Results: Twenty-one patients (15 oropharynx, 4 larynx/hypopharynx, 2 other) underwent 43 adaptation sessions (median, 2). The median ART process time was 23 minutes, median physician time at the console was 27 minutes, and median patient time in the vault was 43.5 minutes. The adapted plan was chosen 93% of the time. The mean volume in each planned target volume (PTV) receiving 100% of the prescription dose for the scheduled versus adapted plan for high-risk PTVs was 87.8% versus 95% ( Conclusions: Online ART is feasible for HNC, with significant improvement in target coverage and homogeneity and a modest decrease in doses to several organs at risk.
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Registered trials
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