ReviewFrontiers in cardiovascular medicine2023
At the heart of the matter: how mental stress and negative emotions affect atrial fibrillation.
Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Integrating Neuroimaging and Machine Learning to Predict Mental Disorder Outcomes: A Systematic Review.Advances in experimental medicine and biology · 2026Pooled it
- Life course adversity and risk of incident atrial fibrillation: causal mediation analysis of psychological distress in the population-based Tromsø Study.BMJ public health · 2026Article
- Heart-brain axis pathophysiological understanding and clinical impact.Frontiers in cardiovascular medicine · 2026Review
- Metabolic Factors Related to Interpersonal Dysfunction in Acromegaly: A Nationwide Cross-Sectional Study in China.CNS neuroscience & therapeutics · 2025Article
- Clustering of electronic health records in atrial fibrillation patients and impact on prognosis and patient trajectories: a UK linked-dataset study.European heart journal. Digital health · 2025Article
- Neuropsychiatry of atrial fibrillation: dementia and beyond.Frontiers in cardiovascular medicine · 2025Review
- Remembering what did not happen: the role of hypnosis in memory recall and false memories formation.Frontiers in psychology · 2025Review
- Autonomic Nervous System Activity before Atrial Fibrillation Onset as Assessed by Heart Rate Variability.Reviews in cardiovascular medicine · 2025Article
- Estimated glucose disposal rate mediates the association between Life's Crucial 9 and congestive heart failure: a population-based study.Frontiers in endocrinology · 2025Article
- The Hidden Heart: Exploring Cardiac Damage Post-Stroke: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- A New Player in the Game: Can Exergame Be of Support in the Management of Atrial Fibrillation?Medicina (Kaunas, Lithuania) · 2024Review
- "Close your eyes and relax": the role of hypnosis in reducing anxiety, and its implications for the prevention of cardiovascular diseases.Frontiers in psychology · 2024Review
- Unveiling the Multifaceted Problems Associated with Dysrhythmia.International journal of molecular sciences · 2023Review
- Sex Related Differences in the Complex Relationship between Coffee, Caffeine and Atrial Fibrillation.Nutrients · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia, affecting 2%-3% of the world's population. Mental and emotional stress, as well as some mental health conditions (e.g., depression) have been shown to significantly impact the heart and have been suggested to act both as independent risk factors and triggers in the onset of AF. In this paper, we review the current literature to examine the role that mental and emotional stress have in the onset of AF and summarise the current knowledge on the interaction between the brain and heart, and the cortical and subcortical pathways involved in the response to stress. Review of the evidence suggests that mental and emotional stress negatively affect the cardiac system, potentially increasing the risk for developing and/or triggering AF. Further studies are required to further understand the cortical and sub-cortical structures involved in the mental stress response and how these interact with the cardiac system, which may help in defining new strategies and interventions to prevent the development of, and improve the management of AF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.