Evidence map›Paper›PMID 37408299›Full record

ArticleHealth services research2023

Comparison of a national commercial pharmacy naloxone data source to state and city pharmacy naloxone data sources-Rhode Island, Massachusetts, and New York City, 2013-2019.

Avik Chatterjee, Shapei Yan, Audrey Lambert, Jake R Morgan, Traci C Green, Philip J Jeng, Ali Jalali, Ziming Xuan, Maxwell Krieger, Brandon D L Marshall and 2 more

Abstract read
In one paragraph

Article in Health services research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Avik ChatterjeeGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Boston Medical Center/Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0001-8437-6774
Shapei YanGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Boston Medical Center/Boston University School of Medicine, Boston, Massachusetts, USA.
Audrey LambertGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Boston Medical Center/Boston University School of Medicine, Boston, Massachusetts, USA.
Jake R MorganBoston University School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-1559-3983
Traci C GreenThe Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, USA.
Philip J JengDepartment of Population Health Sciences, Weill Cornell Medical College, New York City, New York, USA.
Ali JalaliDepartment of Population Health Sciences, Weill Cornell Medical College, New York City, New York, USA.
Ziming XuanBoston University School of Public Health, Boston, Massachusetts, USA.
Maxwell KriegerDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0002-0134-7052
Alexander Y WalleyGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Boston Medical Center/Boston University School of Medicine, Boston, Massachusetts, USA.
Sean M MurphyDepartment of Population Health Sciences, Weill Cornell Medical College, New York City, New York, USA.ORCID 0000-0001-9104-0670

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI Ju Nyeong Park · 2018 to 2026
$23.4M
Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ZACHARY Franklin MEISEL · 2015 to 2026
$20.7M
DAT-18-06 Prevention and Rescue Of Fentanyl and Other Opioid Overdoses Using Optimized Naloxone Distribution Strategies (PROFOUND)U01DA047408 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARSHALL, BRANDON DAVID LEWIS, SCHACKMAN, BRUCE R · 2019 to 2023
$3.5M
Intervention to Increase Naloxone Engagement and Distribution in Community Pharmacies: A Four-State Randomized TrialR01DA045745 · NIDA · BRANDEIS UNIVERSITY · PI GREEN, TRACI C · 2018 to 2021
$3.1M
Improving Naloxone Access and Its Effects on Drug Abuse and OverdosesR01CE002999 · CE · RAND CORPORATION · PI POWELL, DAVID · 2018 to 2020
$1.9M
ACL HHS R01CE002999NCIPC CDC HHS R01 CE002999NIDA NIH HHS P30 DA040500NIDA NIH HHS R01 DA045745NIDA NIH HHS U01 DA047408NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

objectiveAccurate naloxone distribution data are critical for planning and prevention purposes, yet sources of naloxone dispensing data vary by location, and completeness of local datasets is unknown. We sought to compare available datasets in Massachusetts, Rhode Island, and New York City (NYC) to a commercially available pharmacy national claims dataset (Symphony Health Solutions). DATA SOURCES AND STUDY

settingWe utilized retail pharmacy naloxone dispensing data from NYC (2018-2019), Rhode Island (2013-2019), and Massachusetts (2014-2018), and pharmaceutical claims data from Symphony Health Solutions (2013-2019). STUDY

designWe conducted a descriptive, retrospective, and secondary analysis comparing naloxone dispensing events (NDEs) captured via Symphony to NDEs captured by local datasets from the three jurisdictions between 2013 and 2019, when data were available from both sources, using descriptive statistics, regressions, and heat maps. DATA COLLECTION/EXTRACTION

methodsWe defined an NDE as a dispensing event documented by the pharmacy and assumed that each dispensing event represented one naloxone kit (i.e., two doses). We extracted NDEs from local datasets and the Symphony claims dataset. The unit of analysis was the ZIP Code annual quarter. PRINCIPAL

findingsNDEs captured by Symphony exceeded those in local datasets for each time period and location, except in RI following legislation requiring NDEs to be reported to the PDMP. In regression analysis, absolute differences in NDEs between datasets increased substantially over time, except in RI before the PDMP. Heat maps of NDEs by ZIP code quarter showed important variations reflecting where pharmacies may not be reporting NDEs to Symphony or local datasets.

conclusionsPolicymakers must be able to monitor the quantity and location of NDEs in order to combat the opioid crisis. In regions where NDEs are not required to be reported to PDMPs, proprietary pharmaceutical claims datasets may be useful alternatives, with a need for local expertise to assess dataset-specific variability.

Indexed as

Drug OverdoseOpioid-Related DisordersPharmaciesPharmacyHumansInformation SourcesMassachusettsNaloxoneNarcotic AntagonistsNew York CityPharmaceutical PreparationsRetrospective StudiesRhode IslandNaloxoneNarcotic AntagonistsPharmaceutical Preparationsdrug policyharm reductionnaloxoneopioid overdosepharmacy

Identifiers

PMID37408299
PMCPMC10480090

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.