Evidence map›Paper›PMID 37408290›Full record

ArticleAsian spine journal2023

Assessing the Performance of Prognostic Scores in Patients with Spinal Metastases from Lung Cancer Undergoing Non-surgical Treatment.

Van Tri Truong, Fidaa Al-Shakfa, David Roberge, Giuseppina Laura Masucci, Thi Phuoc Yen Tran, Rama Dib, Sung-Joo Yuh, Zhi Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Van Tri TruongDivision of Orthopaedics, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
Fidaa Al-ShakfaDivision of Orthopaedics, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
David RobergeDivision of Radiation Oncology, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
Giuseppina Laura MasucciDivision of Radiation Oncology, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
Thi Phuoc Yen TranResearch Center, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
Rama DibDivision of Orthopaedics, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
Sung-Joo YuhDivision of Neurosurgery, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.
Zhi WangDivision of Orthopaedics, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective study. PURPOSE: The purpose of this study was to see how well the Tomita score, revised Tokuhashi score, modified Bauer score, Van der Linden score, classic Skeletal Oncology Research Group (SORG) algorithm, SORG nomogram, and New England Spinal Metastasis Score (NESMS) predicted 3-month, 6-month, and 1-year survival of non-surgical lung cancer spinal metastases. OVERVIEW OF LITERATURE: There has been no study assessing the performance of prognostic scores for non-surgical lung cancer spinal metastases.

methodsData analysis was carried out to identify the variables that had a significant impact on survival. For all patients with spinal metastasis from lung cancer who received non-surgical treatment, the Tomita score, revised Tokuhashi score, modified Bauer score, Van der Linden score, classic SORG algorithm, SORG nomogram, and NESMS were calculated. The performance of the scoring systems was assessed by using receiver operating characteristic (ROC) curves at 3 months, 6 months, and 12 months. The predictive accuracy of the scoring systems was quantified using the area under the ROC curve (AUC).

resultsA total of 127 patients are included in the present study. The median survival of the population study was 5.3 months (95% confidence interval [CI], 3.7-9.6 months). Low hemoglobin was associated with shorter survival (hazard ratio [HR], 1.49; 95% CI, 1.00-2.23; p =0.049), while targeted therapy after spinal metastasis was associated with longer survival (HR, 0.34; 95% CI, 0.21-0.51; p <0.001). In the multivariate analysis, targeted therapy was independently associated with longer survival (HR, 0.3; 95% CI, 0.17-0.5; p <0.001). The AUC of the time-dependent ROC curves for the above prognostic scores revealed all of them performed poorly (AUC <0.7).

conclusionsThe seven scoring systems investigated are ineffective at predicting survival in patients with spinal metastasis from lung cancer who are treated non-surgically.

Indexed as

AdenocarcinomaArea under curveLung neoplasmsPrognosisSpinal neoplasms

Identifiers

PMID37408290
PMCPMC10460656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.