Evidence map›Paper›PMID 37407974›Full record

SynthesisBMC palliative care2023

Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review.

Carole A Paley, Jason W Boland, Martina Santarelli, Fliss E M Murtagh, Lucy Ziegler, Emma J Chapman

Abstract readSystematic Review
In one paragraph

Synthesis in BMC palliative care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. The effectiveness of non-pharmacological interventions on sleep quality in lung cancer patients: a systematic review and meta-analysis (2015-2025).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  3. The effects of art-making intervention on mind-body and quality of life in adults with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
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  5. Investigating impact of a comprehensive support program on death anxiety among women with breast cancer: a clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  20. Reproductive concerns in young women with cervical cancer: latent profiles and key influencing factors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carole A PaleyUniversity of Leeds, Academic Unit of Palliative Care, Leeds, UK. c.a.paley@leeds.ac.uk.ORCID http://orcid.org/0000-0002-6335-2666
Jason W BolandWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.ORCID http://orcid.org/0000-0001-5272-3057
Martina SantarelliWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.ORCID http://orcid.org/0000-0002-2015-1821
Fliss E M MurtaghWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.ORCID http://orcid.org/0000-0003-1289-3726
Lucy ZieglerUniversity of Leeds, Academic Unit of Palliative Care, Leeds, UK.ORCID http://orcid.org/0000-0001-9563-5014
Emma J ChapmanUniversity of Leeds, Academic Unit of Palliative Care, Leeds, UK.ORCID http://orcid.org/0000-0003-2859-2020

Funding

Yorkshire Cancer Research L412 RESOLVE
6 · The paper itself

Abstract

backgroundPsychological distress is common in patients with cancer; interfering with physical and psychological wellbeing, and hindering management of physical symptoms. Our aim was to systematically review published evidence on non-pharmacological interventions for cancer-related psychological distress, at all stages of the disease.

methodsWe followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The review was registered on PROSPERO (CRD42022311729). Searches were made using eight online databases to identify studies meeting our inclusion criteria. Data were collected on outcome measures, modes of delivery, resources and evidence of efficacy. A meta-analysis was planned if data allowed. Quality was assessed using the Mixed Methods Appraisal Tool (MMAT).

resultsFifty-nine studies with 17,628 participants were included. One third of studies included mindfulness, talking or group therapies. Half of all studies reported statistically significant improvements in distress. Statistically significant intervention effects on distress were most prevalent for mindfulness techniques. Four of these mindfulness studies had moderate effect sizes (d = -0.71[95% CI: -1.04, -0.37] p < 0.001) (d = -0.60 [95% CI: -3.44, -0.89] p < 0.001) (d = -0.77 [CI: -0.146, -1.954] p < 0.01) (d = -0.69 [CI: -0.18, -1.19] p = 0.008) and one had a large effect size (d = -1.03 [95% CI: -1.51, -0.54] p < 0.001). Heterogeneity of studies precluded meta-analysis. Study quality was variable and some had a high risk of bias.

conclusionsThe majority of studies using a mindfulness intervention in this review are efficacious at alleviating distress. Mindfulness-including brief, self-administered interventions-merits further investigation, using adequately powered, high-quality studies. SYSTEMATIC REVIEW REGISTRATION: This systematic review is registered on PROSPERO, number CRD42022311729.

Indexed as

MindfulnessNeoplasmsPsychological DistressHumansDistress; psychological distress; psychological intervention; neoplasms; palliative care; psychosocial oncology

Identifiers

PMID37407974
PMCPMC10324164

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.