Evidence map›Paper›PMID 37407957›Full record

SynthesisBMC women's health2023

A systematic review of the relationship between normal range of serum thyroid-stimulating hormone and bone mineral density in the postmenopausal women.

Xiaoli Zhu, Man Li, Xinying Dong, Fen Liu, Shugang Li, Yifei Hu

Open access · goldAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoli ZhuDepartment of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, No. 10 You' anmenwai Xitoutiao, Fengtai District, Beijing, 100069, China.
Man LiDepartment of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, No. 10 You' anmenwai Xitoutiao, Fengtai District, Beijing, 100069, China.
Xinying DongDepartment of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, No. 10 You' anmenwai Xitoutiao, Fengtai District, Beijing, 100069, China.
Fen LiuHealth Service Department of the Guard Bureau of the Joint Staff Department, Beijing, China.
Shugang LiDepartment of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, No. 10 You' anmenwai Xitoutiao, Fengtai District, Beijing, 100069, China. lishugang@ccmu.edu.cn.
Yifei HuDepartment of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, No. 10 You' anmenwai Xitoutiao, Fengtai District, Beijing, 100069, China. huyifei@yahoo.com.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was adopts meta-analysis in evaluating the correlation between TSH and BMD, as well as osteoporosis in the postmenopausal women with normal thyroid function.

methodsSix databases were searched for articles concerning correlation between TSH and BMD in postmenopausal women. The retrieval time was set from the date of database establishment to November 30, 2020. Revman5.3 and Stata12.0 software were used for meta-analysis.

resultsA total of 19 articles were incorporated. The Summary Fisher' Z of the correlation between TSH and BMD was 0.16, 95% CI (0.00, 0.32), and the correlation coefficient of Summary Fisher' Z conversion was 0.158. Study on the relationship between TSH and osteoporosis based on OR demonstrated that the combined OR was 1.76, 95% CI (1.27, 2.45), P < 0.05. The subgroup analyzing results displayed that the risk of osteoporosis of the subjects from community with low TSH was 1.89, 95% CI (1.43, 2.49). The risk of osteoporosis for subjects with low TSH and from hospitals was 1.36, 95% CI (0.46, 3.99); 1.84 for subjects with low TSH and anti-osteoporosis drugs, 95% CI (1.05, 3.22); and 1.74 for those with low TSH but not taking anti-osteoporosis drugs, 95% CI (1.08, 2.82). The dose-response relationship showed that the risk of osteoporosis tended to decrease when TSH was more than 2.5mIu/L.

conclusionThe serum TSH is positively related with BMD in postmenopausal women, and high TSH (> 2.5 mIu/L) within the normal range is possibly helpful to decrease the risk of osteoporosis in postmenopausal women.

Indexed as

OsteoporosisOsteoporosis, PostmenopausalBone DensityFemaleHumansPostmenopauseReference ValuesThyrotropinThyrotropinBone mineral densityOsteoporosisPostmenopausal womenSerum thyroid-stimulating hormone

Identifiers

PMID37407957
PMCPMC10320894
OpenAlexW4383224934

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.