Evidence map›Paper›PMID 37407917›Full record

ArticleBMC ophthalmology2023

Objective quantification of posterior capsule opacification after cataract surgery with swept-source optical coherence tomography.

Yu Zhou, Jing Xiang, Fang Xu, Ziyuan Jiang, Fang Liu

Abstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yu ZhouDepartment of Ophthalmology, Tenth People's Hospital Affiliated of Tongji University, Shanghai, China.
Jing XiangDepartment of Ophthalmology, Tenth People's Hospital Affiliated of Tongji University, Shanghai, China.
Fang XuDepartment of Ophthalmology, Tenth People's Hospital Affiliated of Tongji University, Shanghai, China.
Ziyuan JiangDepartment of Ophthalmology, Tenth People's Hospital Affiliated of Tongji University, Shanghai, China.
Fang LiuDepartment of Ophthalmology, Tenth People's Hospital Affiliated of Tongji University, Shanghai, China. fangl2000@hotmail.com.

Funding

Clinical research and cultivastion project of Shanghai Municipal Hospital SHDC12019X30Clinical Research Center of Shanghai Tenth People's Hospital Affiliated of Tongji University YNCR2B010Science and Technology Commission of Shanghai Municipality 20142203200
6 · The paper itself

Abstract

purposeTo evaluate the application of swept-source optical coherence tomography (SS-OCT) and pentacam scheimpflug tomography in posterior capsule opacification (PCO) severity assessment.

methodsThe posterior capsule image region segmentation and adaptive threshold algorithm are used to process the SS-OCT scanned image to obtain the posterior capsule thickness (PCT). Scheimpflug tomography reconstructed and analysized by image J software can obtain the average gray value and evaluate the effectiveness with the two methods.

resultOne hundred sixty-two IOL eyes of 101 patients were divided into two groups, laser group (65 eyes) with the mean PCT was 8.0 ± 2.7 pixel unit and the mean gray value of the eyes was 66 ± 33 pixel unit. However, these figures in the control group (97 eyes) were 5.0 ± 0.9 and 11 ± 17. The sensitivity, specificity and area under curve(AUC) of SS-OCT PCT were 85%, 74% and 0.942,the sensitivity, specificity and AUC of Pentacam gray value were 91%, 76% and 0.947, respectively. After using the multivariable model of generalized estimation equation to corrected the dependence of subjects' eyes, it was found that SS-OCT PCT, Pentacam gray value, low vision quality of life questionnaire (LVQ questionnaire) for distance vision, and mobility and lighting dimension were significantly correlated with the PCO score (P = 0.012, P = 0.001, P = 0.005, respectively).

conclusionThe region segmentation and adaptive threshold algorithm of posterior capsule image will accurately quantify the posterior capsule. Computer aided quantifications of posterior capsule are of great significance in the early surgical decision-making of PCO. The average occurrence time of most PCO was around 34 months, and the severity of PCO worsened with increasing postoperative time.

Indexed as

Capsule OpacificationCataractLens Capsule, CrystallineLenses, IntraocularPhacoemulsificationHumansPostoperative ComplicationsQuality of LifeTomography, Optical CoherenceAdaptive threshold algorithmPosterior capsule opacificationPosterior capsule thicknessSwept-source optical coherence tomography

Identifiers

PMID37407917
PMCPMC10324270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.