Evidence map›Paper›PMID 37407889›Full record

ReviewCurrent treatment options in oncology2023

Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers.

Zejie Tian, Hui Li, Zhenhua Liu, Lingyan Yang, Chaoyang Zhang, Jun He, Wenbin Ai, Yunmei Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current treatment options in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. IUCrData · 2024
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zejie TianInstitute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, 28 Changsheng Road, Hengyang City, Hunan Province, 421001, China.
Hui LiInstitute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, 28 Changsheng Road, Hengyang City, Hunan Province, 421001, China.
Zhenhua LiuInstitute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, 28 Changsheng Road, Hengyang City, Hunan Province, 421001, China.
Lingyan YangInstitute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, 28 Changsheng Road, Hengyang City, Hunan Province, 421001, China.
Chaoyang ZhangInstitute of Chemistry & Chemical Engineering, University of South China, Hengyang City, Hunan Province, 421001, China.
Jun HeInstitute of Chemistry & Chemical Engineering, University of South China, Hengyang City, Hunan Province, 421001, China.
Wenbin AiThe Second Affiliated Hospital of University of South China, Hengyang City, Hunan Province, 421001, China.
Yunmei LiuInstitute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, 28 Changsheng Road, Hengyang City, Hunan Province, 421001, China. lymhsm@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementPhotodynamic therapy (PDT) has garnered increasing attention in cancer treatment because of its advantages such as minimal invasiveness and selective destruction. With the development of PDT, impressive progress has been made in the preparation of photosensitizers, particularly porphyrin photosensitizers. However, the limited tissue penetration of the activating light wavelengths and relatively low light energy capture efficiency of porphyrin photosensitizers are two major disadvantages in conventional photosensitizers. Therefore, tissue penetration needs to be enhanced and the light energy capture efficiency of porphyrin photosensitizers improved through structural modifications. The indirect excitation of porphyrin photosensitizers using fluorescent donors (fluorescence resonance energy transfer) has been successfully used to address these issues. In this review, the enhancement of the light energy capture efficiency of porphyrins is discussed.

Indexed as

PhotochemotherapyPorphyrinsHumansPhotosensitizing AgentsPhotosensitizing AgentsPorphyrinsCancerPhotodynamic therapyPhotosensitizersPorphyrin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.