Evidence map›Paper›PMID 37407836›Full record

ArticleBritish journal of cancer2023

Associations of intakes of total protein, protein from dairy sources, and dietary calcium with risks of colorectal, breast, and prostate cancer: a prospective analysis in UK Biobank.

Cody Z Watling, Rebecca K Kelly, Yashvee Dunneram, Anika Knuppel, Carmen Piernas, Julie A Schmidt, Ruth C Travis, Timothy J Key, Aurora Perez-Cornago

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Cody Z WatlingCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. cody.watling@ndph.ox.ac.uk.ORCID 0000-0002-6643-9660
Rebecca K KellyCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Yashvee DunneramCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Anika KnuppelMRC Unit of Lifelong Health and Ageing, University College London, London, United Kingdom.
Carmen PiernasNuffield Department of Primary Care, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-7536-922X
Julie A SchmidtDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Ruth C TravisCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Timothy J KeyCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-2294-307X
Aurora Perez-CornagoCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-5652-356X
University of Oxford · GBAarhus University Hospital · DKMRC Unit for Lifelong Health and Ageing · GB

Funding

Cancer Research UK 29017Cancer Research UK C60192/A28516Cancer Research UK C8221/A29017
6 · The paper itself

Abstract

backgroundEvidence concerning intakes of protein or sources of dairy protein and risks of colorectal, breast, and prostate cancers is inconclusive.

methodsUsing a subsample of UK Biobank participants who completed ≥2 (maximum of 5) 24-h dietary assessments, we estimated intakes of total protein, protein from total dairy products, milk, and cheese, and dietary calcium in 114,217 participants. Hazard ratios (HRs) and 95% confidence intervals (CI) were estimated using multivariable-adjusted Cox regression.

resultsAfter a median of 9.4 years of follow-up, 1193 colorectal, 2024 female breast, and 2422 prostate cancer cases were identified. There were inverse associations of total dairy protein, protein from milk, and dietary calcium intakes with colorectal cancer incidence (HR

conclusionFurther research is needed to understand the mechanisms underlying the relationships of dairy products with cancer risk and the potential roles of dietary protein and calcium.

Indexed as

Colorectal NeoplasmsProstatic NeoplasmsBiological Specimen BanksCalcium, DietaryDairy ProductsDietHumansMaleProspective StudiesRisk FactorsUnited KingdomCalcium, Dietary

Identifiers

PMID37407836
PMCPMC10421858
OpenAlexW4383302118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.