ArticleNature2023
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.
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In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 41 citations in OpenAlex.
- Concepts of RNA virus evolution for the design of better antiviral countermeasures.Nature reviews. Microbiology · 2026Review
- Discovery of 5' NAD capped viral RNAs reveals evolutionary divergent 5' metabolite capping across hepaciviruses.Nature communications · 2026Article
- RNA regulation in plants.Science China. Life sciences · 2026Review
- Molecular basis for noncanonical transcription initiation from NpNature chemical biology · 2026Article
- Molecular insight into 5' RNA capping with NpNature chemical biology · 2026Article
- The capping arms race: evolutionary interplay between IFIT proteins and viral molecular mimicry.Molecular biology reports · 2026Review
- Crystal structure of mouse DXO in complex with the UDP-N-acetylglucosamine cap and molecular mechanism for the decapping reactions.Nucleic acids research · 2026Article
- HIV-driven virome dysbiosis unveils distinct virome features and inter-viral correlations in blood and respiratory niches.Communications biology · 2026Article
- Omnivore RNA pyrophosphatase: a versatile enzyme that efficiently removes diverse protecting groups from the 5' end of RNA.Nucleic acids research · 2026Article
- Characterization of the virus-host RNA-RNA interactome across important human pathogenic RNA viruses.PLoS pathogens · 2026Article
- Hepatitis C Virus 5'UTR Sequences That Bind eIF3 and Ribosomal 40S Subunits Confer Stimulation of Minus-Strand RNA Synthesis.International journal of molecular sciences · 2026Article
- Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs.Nature biotechnology · 2026Article
- NAD+ capping of sibD transcripts in E. coli is mediated by its minimal promoter and enhanced by ppGpp.Nucleic acids research · 2026Article
- The Danish Database for Hepatitis B and C (DANHEP): A Nationwide, Prospective, Ongoing Cohort Study.Clinical epidemiology · 2026Article
- Hepatitis C virus NS3 helicase contributes to (-) strand RNA synthesis.Nature communications · 2025Article
- A two-step mechanism for RIG-I activation by influenza virus mvRNAs.Science advances · 2025Article
- Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA.Nature communications · 2025Article
- CompasSeq: epitranscriptome-wide percentage assessment of metabolite-capped RNA at the transcript resolution.Nature communications · 2025Article
- Extracellular exosomal RNAs are glyco-modified.Nature cell biology · 2025Article
- Viral oncogenesis in cancer: from mechanisms to therapeutics.Signal transduction and targeted therapy · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 2 institutions in 3 countries.
Anna V Sherwood *Section for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0001-7153-8420
Lizandro R Rivera-Rangel *Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Line A RybergCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Helena S LarsenCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Klara M AnkerSection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0002-2459-8583
Rui CostaCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0003-3048-6366
Cathrine B VågbøProteomics and Modomics Experimental Core (PROMEC), Norwegian University of Science and Technology and the Central Norway Regional Health Authority, Trondheim, Norway.
Eva JakljevičCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0003-3657-1254
Long V PhamCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Carlota Fernandez-AntunezCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Gabriele IndrisiunaiteSection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.
Agnieszka Podolska-CharlerySection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0003-3789-2746
Julius E R GrothenSection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0002-1857-6134
Nicklas W LangvadSection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0002-9980-5030
Nicolas FossatCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0002-0161-6507
Anna OffersgaardCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0002-7748-2840
Amal Al-ChaerSection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.
Louise NielsenCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Anna KuśnierczykProteomics and Modomics Experimental Core (PROMEC), Norwegian University of Science and Technology and the Central Norway Regional Health Authority, Trondheim, Norway.ORCID 0000-0003-3517-3481
Christina SølundDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0002-3133-2724
Judith M GottweinCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0003-2805-0256
Kenn HolmbeckCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Sandro BottaroSection for Biomolecular Sciences, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0003-1606-890X
Santseharay RamirezCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0003-3699-1814
Jens BukhCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark. jbukh@sund.ku.dk.ORCID 0000-0002-7815-4806
Troels K H ScheelCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark. tscheel@sund.ku.dk.ORCID 0000-0003-1545-4067
Jeppe VintherSection for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark. jvinther@bio.ku.dk.ORCID 0000-0002-3847-3853
University of Copenhagen · DKNorwegian University of Science and Technology · NO
Funding
European Research Council 802899
Abstract
RNA viruses have evolved elaborate strategies to protect their genomes, including 5' capping. However, until now no RNA 5' cap has been identified for hepatitis C virus
Indexed as
Flavin-Adenine DinucleotideHepacivirusRNA CapsRNA, ViralAnimalsChimeraDEAD Box Protein 58Hepatitis CHumansInnate Immunity RecognitionLiverMiceReceptors, ImmunologicRNA-Dependent RNA PolymeraseRNA StabilityVirus ReplicationDEAD Box Protein 58Flavin-Adenine DinucleotideReceptors, ImmunologicRIGI protein, humanRNA CapsRNA-Dependent RNA PolymeraseRNA, Viral
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.