ArticleNature2023
Cooperation between bHLH transcription factors and histones for DNA access.
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Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
15.4field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 100 citations in OpenAlex.
- Feeding microbes to feed the Gut: inulin reprograms intestinal epithelial metabolism and proliferation through HIF1α.Gut microbes · 2026Review
- Stable clocks, rewired rhythms: circadian remodeling in skeletal muscle during aging, cachexia, and type 2 diabetes.Life metabolism · 2026Review
- Time matters: circadian genetics and the molecular logic of human health and disease.Nature reviews. Genetics · 2026Review
- Article
- Nucleosomes and IDRs suppress promiscuous GCN4 binding on minichromosomes.Nature structural & molecular biology · 2026Article
- CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators.Nature cell biology · 2026Article
- Research Advances on the Functions of Transcriptional Regulators in Filamentous Fungi.Microorganisms · 2026Review
- Two essential criteria for transcription factor footprint discovery using V-plot.Molecular systems biology · 2026Article
- MYC in Oncogenesis and Therapeutic Implications.MedComm · 2026Review
- Cumulative transcription factor binding and p300-mediated histone acetylation drive enhancer activation frequency.Nature genetics · 2026Article
- mTOR signaling contributes to system-driven rhythmic gene expression in mouse liver.Science advances · 2026Article
- A Chromatin Biology Assessment of AlphaFold3.bioRxiv : the preprint server for biology · 2026Article
- The CLOCK-BMAL1 complex in circadian regulation: structure, mechanisms, and therapeutic targeting.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- Context-dependent variability of HIF heterodimers influences interactions with macromolecular and small molecule partners.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The PER2:BRCA1:POU2F1(OCT-1) ternary complex represents a multi-component scaffold model for circadian gene regulation.Neurobiology of sleep and circadian rhythms · 2026Article
- Small Molecule Regulation of CLOCK:BMAL1 DNA Binding Activity.bioRxiv : the preprint server for biology · 2026Article
- Integration of circadian and hypoxia signaling via non-canonical heterodimerization.FEBS letters · 2026Review
- Interplay between circadian and other transcription factors-Implications for cycling transcriptome reprogramming.FEBS letters · 2026Review
- Disordered but rhythmic-the role of intrinsic protein disorder in eukaryotic circadian timing.FEBS letters · 2026Review
- Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets.FEBS letters · 2026Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 9 institutions in 4 countries.
Alicia K Michael *Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.ORCID 0000-0002-6080-839X
Lisa Stoos *Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Priya CrosbyDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA, USA.
Nikolas EggersBiomedical Center, Molecular Biology Division, Ludwig-Maximilians-Universität, Munich, Germany.ORCID 0000-0002-0256-1982
Xinyu Y NieDepartment of Biology, Center for Biological Clock Research, Texas A&M University, College Station, TX, USA.
Kristina MakashevaInstitute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID 0000-0002-0645-6848
Martina MinnichResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.ORCID 0000-0003-4677-3300
Kelly L HealyDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL, USA.
Joscha WeissFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.ORCID 0000-0002-4149-0478
Georg KempfFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Simone CavadiniFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Lukas KaterFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Jan SeebacherFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Luca VecchiaFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Deyasini ChakrabortyFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Luke IsbelFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.ORCID 0000-0002-5270-4347
Ralph S GrandFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Florian AnderschResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.
Jennifer L FribourghDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA, USA.
Dirk SchübelerFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Johannes ZuberResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.ORCID 0000-0001-8810-6835
Andrew C LiuDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0003-1927-0900
Peter B BeckerBiomedical Center, Molecular Biology Division, Ludwig-Maximilians-Universität, Munich, Germany.ORCID 0000-0001-7186-0372
Beat FierzInstitute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID 0000-0002-2991-3044
Carrie L PartchDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA, USA.ORCID 0000-0002-4677-2861
Jerome S MenetDepartment of Biology, Center for Biological Clock Research, Texas A&M University, College Station, TX, USA.ORCID 0000-0002-7682-0967
Nicolas H ThomäFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland. thoman@fmi.ch.ORCID 0000-0003-2685-906X
Friedrich Miescher Institute · CHUniversity of Basel · CHResearch Institute of Molecular Pathology · ATUniversity of California, Santa Cruz · USÉcole Polytechnique Fédérale de Lausanne · CHLudwig-Maximilians-Universität München · DETexas A&M University · USUniversity of Florida · USFriedrich Miescher Institute · CH
Funding
Molecular, Cellular and Physiological Mechanisms of the Mammalian Circadian ClockR01NS054794 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI HOGENESCH, JOHN B, LIU, ANDREW C. · 2007 to 2022
$8.1MStructures and mechanisms of circadian rhythms from cyanobacteria to humansR35GM141849 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2021 to 2025
$4.6MExploring the structural basis for 24-hour timekeeping in mammalsR01GM107069 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2013 to 2020
$3.2MCooperation between transcription factors and its role in the regulation of rhythmic enhancer activity by the circadian clockR01GM145737 · NIGMS · TEXAS A&M UNIVERSITY · PI MENET, JEROME · 2022 to 2025
$1.3MNIGMS NIH HHS R01 GM107069NIGMS NIH HHS R01 GM145737NIGMS NIH HHS R35 GM141849NINDS NIH HHS R01 NS054794
Abstract
The basic helix-loop-helix (bHLH) family of transcription factors recognizes DNA motifs known as E-boxes (CANNTG) and includes 108 members
Indexed as
Basic Helix-Loop-Helix ProteinsDNAHistonesAllosteric RegulationARNTL Transcription FactorsBasic-Leucine Zipper Transcription FactorsCLOCK ProteinsHelix-Loop-Helix MotifsLeucine ZippersNucleosomesOctamer Transcription Factor-3Protein BindingProtein MultimerizationProto-Oncogene Proteins c-mycARNTL Transcription FactorsBasic Helix-Loop-Helix ProteinsBasic-Leucine Zipper Transcription FactorsCLOCK ProteinsDNAHistonesMyc associated factor XNucleosomesOctamer Transcription Factor-3Proto-Oncogene Proteins c-myc
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.