Evidence map›Paper›PMID 37407813›Full record

ArticleNature2023

Evolution of a minimal cell.

R Z Moger-Reischer, J I Glass, K S Wise, L Sun, D M C Bittencourt, B K Lehmkuhl, D R Schoolmaster, M Lynch, J T Lennon

Erratum issuedOpen access · hybridAbstract readComparative Study
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 94 citations in OpenAlex.

  1. Evolution expresses the second law of thermodynamics in action.Journal of the Royal Society, Interface · 2026
    Article
  2. Review
  3. Let There be Light! Light as an Engine and Regulator in Synthetic Cells.Angewandte Chemie (International ed. in English) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Design biology and mind-body health.Journal, genetic engineering & biotechnology · 2025
    Review
  14. Review
  15. Ancestral Protein-Based Lighting.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  16. Article
  17. Article
  18. The design and engineering of synthetic genomes.Nature reviews. Genetics · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

R Z Moger-ReischerDepartment of Biology, Indiana University, Bloomington, IN, USA.
J I GlassJ. Craig Venter Institute, La Jolla, CA, USA.
K S WiseJ. Craig Venter Institute, La Jolla, CA, USA.
L SunJ. Craig Venter Institute, La Jolla, CA, USA.
D M C BittencourtJ. Craig Venter Institute, La Jolla, CA, USA.ORCID 0000-0002-3137-6567
B K LehmkuhlDepartment of Biology, Indiana University, Bloomington, IN, USA.
D R SchoolmasterUS Geological Survey, Wetland and Aquatic Research Center, Lafayette, LA, USA.ORCID 0000-0003-0910-4458
M LynchArizona State University, Tempe, AZ, USA.ORCID 0000-0002-1653-0642
J T LennonDepartment of Biology, Indiana University, Bloomington, IN, USA. lennonj@indiana.edu.ORCID 0000-0003-3126-6111
J. Craig Venter Institute · USIndiana University Bloomington · USArizona State University · USBrazilian Agricultural Research Corporation · BRGenomics Institute of the Novartis Research Foundation · USUnited States Geological Survey · US

Funding

Causes and Population-genetic Consequences of Molecular VariationR35GM122566 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Michael R LYNCH · 2017 to 2026
$7.7M
Serial Block Face Scanning Electron MicroscopeS10OD023501 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI INNES, ROGER W. · 2017 to 2017
$599k
NIGMS NIH HHS R35 GM122566NIH HHS S10 OD023501
6 · The paper itself

Abstract

Possessing only essential genes, a minimal cell can reveal mechanisms and processes that are critical for the persistence and stability of life

Indexed as

Evolution, MolecularGenes, EssentialGenome, BacterialMycoplasma mycoidesSynthetic BiologyBiotechnologyCell DivisionCell SizeEpistasis, GeneticGenetic FitnessMutationSelection, GeneticSymbiosisTubulinTubulin

Identifiers

PMID37407813
PMCPMC10396959
OpenAlexW4383198532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.