Evidence map›Paper›PMID 37407720›Full record

Observational studyWorld journal of urology2023

Late complications and 5 years outcomes of robotic partial nephrectomy in France: prospective assessment in the French Kidney Cancer Research Network (UroCCR 10).

Gaëlle Margue, Alexandre Ingels, Karim Bensalah, Nicolas Doumerc, Christophe Vaessen, Morgan Roupret, François Audenet, Arnaud Mejean, Franck Bruyere, Jonathan Olivier and 10 more

Registry-linked trialAbstract readObservational StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03292549 (RObotic PArtial Nephrectomy National Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03292549 completednot on this map

RObotic PArtial Nephrectomy National Study (RoPaN Study)

TypeobservationalSponsorUniversity Hospital, BordeauxRan2014 to 2016Enrolled452ConditionsKidney CancerArmsRobotic partial surgery
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 1 country.

Gaëlle MargueService d'urologie, Urology Department, Bordeaux University Hospital, CHU de Bordeaux, Place Amelie Raba Leon, 33000, Bordeaux, France. gaelle.margue@chu-bordeaux.Fr.ORCID http://orcid.org/0000-0001-5311-1597
Alexandre IngelsUrology Department, Henri Mondor University Hospital, APHP, Paris, France.
Karim BensalahUrology Department, Rennes University Hospital, Rennes, France.
Nicolas DoumercUrology Department, Toulouse University Hospital, Toulouse, France.
Christophe VaessenUrology Department, Pitié-Saplétrière Hospital, APHP, Paris, France.
Morgan RoupretUrology Department, Pitié-Saplétrière Hospital, APHP, Paris, France.
François AudenetUrology Department, European Georges Pompidou Hospital, Paris, France.
Arnaud MejeanUrology Department, European Georges Pompidou Hospital, Paris, France.
Franck BruyereUrology Department, Tours University Hospital, Tours, France.
Jonathan OlivierUrology Department, Lille University Hospital, Lille, France.
Hervé BaumertUrology Department, Saint Joseph Hospital, Paris, France.
Constance MichelUrology Department, Saint Joseph Hospital, Paris, France.
Philippe PaparelUrology Department, Lyon Sud University Hospital, Lyon, France.
Bastien ParierUrology Department, Bicêtre University Hospital, Le Kremlin-Bicêtre, France.
Philippe SebeUrology Department, Hospital Group Diaconesses Croix Saint-Simon, Paris, France.
Jean-Alexandre LongUrology Department, Grenoble Alpes University Hospital, Grenoble, France.
Hervé LangUrology Department, Strasbourg University Hospital, Strasbourg, France.
Thierry LebretUrology Department, Foch Hospital, Paris Saclay University, Suresnes, France.
Jean-Jacques PatardUrology Department, Mont de Marsan Hospital, Mont de Marsan, France.
Jean-Christophe BernhardService d'urologie, Urology Department, Bordeaux University Hospital, CHU de Bordeaux, Place Amelie Raba Leon, 33000, Bordeaux, France.
Centre Hospitalier Universitaire de Bordeaux · FRHôpital Européen Georges-Pompidou · FRHôpital Saint Joseph · FRSorbonne Université · FRAssistance Publique – Hôpitaux de Paris · FRBicêtre Hospital · FRCentre Hospitalier Universitaire de Rennes · FRGroupe Hospitalier Diaconesses Croix Saint-Simon · FRHospices Civils de Lyon · FRUniversité de Strasbourg · FRUniversité de Tours · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FRUniversité Grenoble Alpes · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the practice of robotic-assisted partial nephrectomy (RAPN) in France and prospectively assess the late complications and long-term outcomes.

methodsProspective, multicenter (n = 16), observational study including all patients diagnosed with a renal tumor who underwent RAPN. Preoperative, intraoperative, postoperative, and follow-up data were collected and stored in the French research network for kidney cancer database (UroCCR). Patients were included over a period of 12 months, then followed for 5 years.

resultsIn total, 466 patients were included, representing 472 RAPN. The mean tumor size was 3.4 ± 1.7 cm, most of moderate complexity (median PADUA and RENAL scores of 8 [7-10] and 7 [5-9]). Indication for nephron-sparing surgery was relative in 7.1% of cases and imperative in 11.8%. Intraoperative complications occurred in 6.8% of patients and 4.2% of RAPN had to be converted to open surgery. Severe postoperative complications were experienced in 2.3% of patients and late complications in 48 patients (10.3%), mostly within the first 3 months and mainly comprising vascular, infectious, or parietal complications. At 5 years, 29 patients (6.2%) had chronic kidney disease upstaging, 21 (4.5%) were diagnosed with local recurrence, eight (1.7%) with contralateral recurrence, 25 (5.4%) with metastatic progression, and 10 (2.1%) died of the disease.

conclusionOur results reflect the contemporary practice of French expert centers and is, to our knowledge, the first to provide prospective data on late complications associated with RAPN. We have shown that RAPN provides good functional and oncologic outcomes while limiting short- and long-term morbidity.

trial registrationNCT03292549.

Indexed as

Kidney NeoplasmsRobotic Surgical ProceduresFranceHumansNephrectomyPostoperative ComplicationsProspective StudiesRetrospective StudiesTreatment OutcomeHemostasisKidney cancerPartial nephrectomyRobotic surgery

Identifiers

PMID37407720
OpenAlexW4383197111

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.