ArticleScientific reports2023
Extensive reduction in choroidal thickness after photodynamic therapy in eyes with central serous chorioretinopathy.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 16 citations in OpenAlex.
- Anterior Suprachoroidal Fluid Following Photodynamic Therapy for Chronic CSC: An Anterior-Segment Optical Coherence Tomography Study.Ophthalmology and therapy · 2026Article
- Evaluation of choriocapillaris perfusion changes in chronic central serous chorioretinopathy following Half-Dose photodynamic therapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Evaluation of longitudinal changes in choroidal thickness during pregnancy and postpartum using widefield swept-source optical coherence tomography.Scientific reports · 2025Observational
- Reduction in choroidal thickness associated with the progression of pachychoroid spectrum diseases.Japanese journal of ophthalmology · 2025Article
- Effectiveness and safety of repeated photodynamic therapy in recurrent central serous chorioretinopathy.Acta ophthalmologica · 2025Article
- Preferential Locations of Polypoidal Lesions and Adjacent Pigment Epithelium Detachments in Polypoidal Choroidal Vasculopathy in a Japanese Population.Investigative ophthalmology & visual science · 2025Article
- One-year choroidal thickness changes after photodynamic therapy for central serous chorioretinopathy evaluated by widefield optical coherence tomography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Central serous chorioretinopathy and the sclera: what we have learned so far.Japanese journal of ophthalmology · 2024Review
- The Evaluation of Change in Choroidal Circulation Time before and after Half-Dose Photodynamic Therapy in Central Serous Chorioretinopathy Using Wide-Field Indocyanine Green Angiography.Journal of clinical medicine · 2024Article
- Wide-Field Choroidal Thickness Analysis after Half-Fluence Photodynamic Therapy Combined with Intravitreal Aflibercept Injection in Pachychoroid Neovasculopathy.Journal of clinical medicine · 2024Article
- Attenuation of irradiated choroid and its regional vortex veins in central serous chorioretinopathy after photodynamic therapy.Scientific reports · 2023Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined the effect of reduced fluence (rf)-photodynamic therapy (PDT) of the macular area on the wide-field choroidal thickness in 20 eyes with central serous chorioretinopathy (CSC) and 20 age- and sex-matched control eyes. The choroidal thickness at the posterior pole was measured before and after rf-PDT, using a grid with inner and outer rings, each divided into superotemporal, inferotemporal, superonasal, and inferonasal quadrants, respectively, making up a total of nine subfields including the central 3 mm ring. Before treatment, all eyes showed wide-field choroidal thickening from the dilated vortex vein ampulla to the fovea, along the course of the vein. After rf-PDT of the macular area, the choroidal thickness significantly decreased, not only in the irradiated macular area but also outside the arcade vessels in all quadrants (p < 0.001 for all inner subfields; p = 0.035 and p = 0.024 for the outer superonasal and inferonasal subfields, respectively; p < 0.001 and p = 0.004 for the outer superotemporal and inferotemporal subfields, respectively). For control eyes, the choroidal thickness did not differ between the initial visit and follow-up 1.2 ± 0.7 months after the initial visit (p > 0.05 for all subfields). These findings provide new insights into the pathogenesis of CSC and explain the reasons for the effectiveness of rf-PDT for this condition.
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