ArticleScientific reports2023
AFM methods for studying the morphology and micromechanical properties of the membrane of human buccal epithelium cell.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Deep Learning-driven Automatic Nuclei Segmentation of Label-free Live Cell Chromatin-sensitive Partial Wave Spectroscopic Microscopy Imaging.bioRxiv : the preprint server for biology · 2024Article
- Stereoscopic Imaging of Single Molecules at Plasma Membrane of Single Cell Using Photoreduction-Assisted Electrochemistry.Research (Washington, D.C.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using AFM methods in air under normal conditions in a wide range of local force effects ([Formula: see text]< 40 μN) the relief, functional micromechanical properties (elasticity coefficient [Formula: see text], Young's modulus [Formula: see text], elastic [Formula: see text] and plastic [Formula: see text] deformations) and adhesive properties (work [Formula: see text] of adhesive forces [Formula: see text]) of the membranes of living adult cells of human buccal epithelium were studied in the presence of a protective layer < 100 nm of buffer solution that prevented the cells from drying. Almost all geometric and functional characteristics of the membrane in the local approximation at the micro- and nanolevels are affected by size effects and obey the laws of fractal geometry. The Brownian multifractal relief of the membrane is characterized by dimension [Formula: see text] < 2.56 and irregularities < 500 nm vertically and < 2 μm horizontally. Its response to elastic (≤ 6 nN), active (6-21 nN), or passive (> 21 nN) stimulation ([Formula: see text]) is a non-trivial selective process and exhibits a correspondingly elastic ([Formula: see text] 67.4 N/m), active ([Formula: see text] 80.2 N/m) and passive ([Formula: see text] 84.5 N/m) responses. [Formula: see text] and [Formula: see text] depend on [Formula: see text]. Having undergone slight plastic deformations [Formula: see text] < 300 nm, the membrane is capable of restoring its shape. We mapped ([Formula: see text], [Formula: see text] = 2.56; [Formula: see text], [Formula: see text] = 2.68; [Formula: see text], [Formula: see text] = 2.42, [Formula: see text] and [Formula: see text]) indicating its complex cavernous structure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.