Evidence map›Paper›PMID 37407595›Full record

ArticleScientific reports2023

Multimodal deep learning for COVID-19 prognosis prediction in the emergency department: a bi-centric study.

Franca Dipaola, Mauro Gatti, Alessandro Giaj Levra, Roberto Menè, Dana Shiffer, Roberto Faccincani, Zainab Raouf, Antonio Secchi, Patrizia Rovere Querini, Antonio Voza and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Franca DipaolaInternal Medicine, Humanitas Clinical and Research Center, IRCCS, Humanitas Research Hospital, Humanitas University, Via A. Manzoni, 56, 20089, Rozzano, Milan, Italy.
Mauro GattiIBM, Milan, Italy.
Alessandro Giaj LevraDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Italy.
Roberto MenèDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Dana ShifferDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Italy.
Roberto FaccincaniEmergency Department, Humanitas Mater Domini, Castellanza, Varese, Italy.
Zainab RaoufIRCCS-Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy.
Antonio SecchiIRCCS-Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy.
Patrizia Rovere QueriniIRCCS-Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy.
Antonio VozaDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Italy.
Salvatore BadalamentiInternal Medicine, Humanitas Clinical and Research Center, IRCCS, Humanitas Research Hospital, Humanitas University, Via A. Manzoni, 56, 20089, Rozzano, Milan, Italy.
Monica SolbiatiEmergency Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore, Milan, Italy.
Giorgio CostantinoEmergency Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore, Milan, Italy.
Victor SavevskiAI Center, IRCCS - Humanitas Research Hospital, Via Manzoni 56, Rozzano, Italy.
Raffaello FurlanInternal Medicine, Humanitas Clinical and Research Center, IRCCS, Humanitas Research Hospital, Humanitas University, Via A. Manzoni, 56, 20089, Rozzano, Milan, Italy. raffaello.furlan@hunimed.eu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting clinical deterioration in COVID-19 patients remains a challenging task in the Emergency Department (ED). To address this aim, we developed an artificial neural network using textual (e.g. patient history) and tabular (e.g. laboratory values) data from ED electronic medical reports. The predicted outcomes were 30-day mortality and ICU admission. We included consecutive patients from Humanitas Research Hospital and San Raffaele Hospital in the Milan area between February 20 and May 5, 2020. We included 1296 COVID-19 patients. Textual predictors consisted of patient history, physical exam, and radiological reports. Tabular predictors included age, creatinine, C-reactive protein, hemoglobin, and platelet count. TensorFlow tabular-textual model performance indices were compared to those of models implementing only tabular data. For 30-day mortality, the combined model yielded slightly better performances than the tabular fastai and XGBoost models, with AUC 0.87 ± 0.02, F1 score 0.62 ± 0.10 and an MCC 0.52 ± 0.04 (p < 0.32). As for ICU admission, the combined model MCC was superior (p < 0.024) to the tabular models. Our results suggest that a combined textual and tabular model can effectively predict COVID-19 prognosis which may assist ED physicians in their decision-making process.

Indexed as

COVID-19Deep LearningEmergency Service, HospitalHospitalizationHumansPrognosisRetrospective Studies

Identifiers

PMID37407595
PMCPMC10322913

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.