Evidence map›Paper›PMID 37406880›Full record

ArticleCanadian journal of diabetes2023

Risk Factors for Type 2 Diabetes in the Multiethnic Cohort.

Gertraud Maskarinec, Bruce S Kristal, Lynne R Wilkens, Gino Quintal, David Bogumil, Veronica W Setiawan, Loïc Le Marchand

Open access · greenAbstract read
In one paragraph

Article in Canadian journal of diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gertraud MaskarinecPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, Hawaii, United States. Electronic address: gertraud@cc.hawaii.edu.
Bruce S KristalDivision of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States.
Lynne R WilkensPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, Hawaii, United States.
Gino QuintalPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, Hawaii, United States.
David BogumilPreventive Medicine, University of Southern California, Los Angeles, California, United States.
Veronica W SetiawanPreventive Medicine, University of Southern California, Los Angeles, California, United States.
Loïc Le MarchandPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, Hawaii, United States.
University of Hawaiʻi at Mānoa · USUniversity of Southern California · USBrigham and Women's Hospital · US

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
University of Guam/Cancer Research Center of Hawaii Partnership (2 of 2)U54CA143728 · NCI · UNIVERSITY OF GUAM · PI RACHAEL T LEON GUERRERO · 2009 to 2026
$20.1M
Recruitment and Data CollectionP01CA168530 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI LE MARCHAND, LOIC · 2012 to 2016
$19.9M
University of Guam/Cancer Research Center of Hawaii Partnership (1 of 2)U54CA143727 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Brenda Yukari Hernandez, RACHAEL T LEON GUERRERO · 2009 to 2026
$19.1M
Lipidomics Biomarkers Link Sleep Restriction to Adiposity Phenotype, Diabetes, and Cardiovascular RiskR01HL140335 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KRISTAL, BRUCE S · 2018 to 2021
$3.4M
Multidisciplinary Training in Ethnic Diversity and Cancer DisparitiesT32CA229110 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2019 to 2023
$2.1M
NCI NIH HHS P01 CA168530NCI NIH HHS P30 CA071789NCI NIH HHS T32 CA229110NCI NIH HHS U01 CA164973NCI NIH HHS U54 CA143727NCI NIH HHS U54 CA143728NHLBI NIH HHS R01 HL140335
6 · The paper itself

Abstract

objectivesIn this report, we investigated the association between established risk factors and type 2 diabetes (T2D) across 5 distinct ethnic groups and explored differences according to T2D definition within the Multiethnic Cohort (MEC) Study.

methodsUsing the full MEC, with participants in Hawaii and Los Angeles (N=172,230), we applied Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). All participants completed questionnaires asking about demographics, anthropometrics, lifestyle factors, and regular diet. T2D status was determined from self-reported diagnosis/medication and Medicare claims. We assessed the associations between well-established risk factors and T2D in the full cohort, after stratification by ethnic group, according to the T2D definition, and in a biorepository subset. Effect modification by ethnicity was evaluated using Wald's tests.

resultsOverall, 46,500 (27%) participants had an incident T2D diagnosis after a mean follow-up of 17.1±6.9 years. All predictors were significantly associated with T2D: overweight (HR=1.74), obesity (HR=2.90), red meat intake (HR=1.15), short (HR=1.04) and long (HR=1.08) sleep duration, and smoking (HR=1.26) predicted a significantly higher T2D incidence, whereas coffee (HR=0.90) and alcohol (HR=0.78) consumption, physical activity (HR=0.89), and diet quality (HR=0.96) were associated with lower T2D incidence. The strength of these associations was similar across ethnic groups with noteworthy disparities for overweight/obesity, physical activity, alcohol intake, coffee consumption, and diet quality.

conclusionsThese findings confirm the importance of known risk factors for T2D across ethnic groups, but small differences were detected that may contribute to disparate incidence rates in some ethnic groups, especially for obesity and physical activity.

Indexed as

Diabetes Mellitus, Type 2AgedCoffeeDietHumansIncidenceMedicareObesityOverweightRisk FactorsUnited StatesCoffeeanalyse de surviecohort studiesdiabète de type 2ethnicitéethnicityétudes de cohorteslifestylemode de viesurvival analysistype 2 diabetes

Identifiers

PMID37406880
PMCPMC10761589
OpenAlexW4382929906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.