Evidence map›Paper›PMID 37406344›Full record

ReviewAnnual review of microbiology2023

Unique Properties of Apicomplexan Mitochondria.

Ian M Lamb, Ijeoma C Okoye, Michael W Mather, Akhil B Vaidya

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. TheMolecular biology of the cell · 2025
    Article
  11. Article
  12. Article
  13. ThebioRxiv : the preprint server for biology · 2024
    Article
  14. Detailing organelle division and segregation inbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ian M LambCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; email: av27@drexel.edu.
Ijeoma C OkoyeCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; email: av27@drexel.edu.
Michael W MatherCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; email: av27@drexel.edu.
Akhil B VaidyaCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; email: av27@drexel.edu.
Drexel University · US

Funding

ORGANELLE GENOMES OF MALARIAL PARASITESR01AI028398 · NIAID · MCP HAHNEMANN UNIVERSITY · PI AKHIL B VAIDYA · 1989 to 2026
$10.1M
Optimizing ELQs for Treatment and Prevention of MalariaR01AI100569 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Michael Kevin RISCOE · 2014 to 2026
$8.0M
Molecular Pathways Affected by Drugs that Disrupt Na+ Homeostasis in Malaria ParasitesR01AI132508 · NIAID · DREXEL UNIVERSITY · PI AKHIL B VAIDYA · 2017 to 2026
$5.7M
Advancing Fast-acting Antimalarials that Disrupt Na+ Homeostasis in ParasitesR01AI154499 · NIAID · DREXEL UNIVERSITY · PI KORTAGERE, SANDHYA, VAIDYA, AKHIL B · 2020 to 2024
$3.7M
NIAID NIH HHS R01 AI028398NIAID NIH HHS R01 AI100569NIAID NIH HHS R01 AI132508
6 · The paper itself

Abstract

Apicomplexan parasites constitute more than 6,000 species infecting a wide range of hosts. These include important pathogens such as those causing malaria and toxoplasmosis. Their evolutionary emergence coincided with the dawn of animals. Mitochondrial genomes of apicomplexan parasites have undergone dramatic reduction in their coding capacity, with genes for only three proteins and ribosomal RNA genes present in scrambled fragments originating from both strands. Different branches of the apicomplexans have undergone rearrangements of these genes, with

Indexed as

MalariaToxoplasmaAnimalsBiological EvolutionMitochondriaantiparasitic drugsATP synthaseelectron transport complexesMyzozoaPlasmodiumToxoplasma

Identifiers

PMID37406344
PMCPMC11156254
OpenAlexW4383216095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.