Evidence map›Paper›PMID 37406141›Full record

ArticleAIDS education and prevention : official publication of the International Society for AIDS Education2023

Fostering Access to PrEP Among Adolescent Girls and Young Women Aged 16 to 24 Years at High Risk of HIV Through the DREAMS Initiative in Four Districts in Zambia.

Julian Chipukuma, Brianna Lindsay, Linah K Mwango, Pawel Olowski, Caitlin Baumhart, Kalima Tembo, Adebayo A Olufunso, Christine Bwale, Priscilla Makasa, Monde Muchoka and 16 more

Abstract read
In one paragraph

Article in AIDS education and prevention : official publication of the International Society for AIDS Education, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Julian ChipukumaMaryland Global Initiatives Corporation Zambia, Lusaka, Zambia.
Brianna LindsayMaryland Global Initiatives Corporation Zambia, Lusaka, Zambia.
Linah K MwangoCiheb Zambia, Lusaka, Zambia.
Pawel OlowskiMaryland Global Initiatives Corporation Zambia, Lusaka, Zambia.
Caitlin BaumhartCenter for International Health, Education, and Biosecurity, University of Maryland School of Medicine, Baltimore, Maryland.
Kalima TemboMaryland Global Initiatives Corporation Zambia, Lusaka, Zambia.
Adebayo A OlufunsoMaryland Global Initiatives Corporation Zambia, Lusaka, Zambia.
Christine BwaleCiheb Zambia, Lusaka, Zambia.
Priscilla MakasaCiheb Zambia, Lusaka, Zambia.
Monde MuchokaCiheb Zambia, Lusaka, Zambia.
Salina TemboCiheb Zambia, Lusaka, Zambia.
Waitolo MbokileCiheb Zambia, Lusaka, Zambia.
Comfort PandaCiheb Zambia, Lusaka, Zambia.
Siphiwe MalupandeCiheb Zambia, Lusaka, Zambia.
Richard LubindaCiheb Zambia, Lusaka, Zambia.
Brenda BwembeloCiheb Zambia, Lusaka, Zambia.
Everess FunduluCiheb Zambia, Lusaka, Zambia.
Chimpinde MunsongoMinistry of Health, Zambia.
Kelvin WatalaMinistry of Health, Zambia.
Bupe MusondaMinistry of Health, Zambia.
Omega ChituwoU.S. Centers for Disease Control and Prevention, Lusaka, Zambia.
Jackson OkukuU.S. Centers for Disease Control and Prevention, Lusaka, Zambia.
Annie MwilaU.S. Centers for Disease Control and Prevention, Lusaka, Zambia.
Carlos MuleyaU.S. Centers for Disease Control and Prevention, Lusaka, Zambia.
Pragna PatelDivision of Global HIV and TB, Centers for Disease Control and Prevention, Atlanta, Georgia.
Cassidy W ClaassenMaryland Global Initiatives Corporation Zambia, Lusaka, Zambia.

Funding

CGH CDC HHS U2G GH000113Intramural CDC HHS CC999999PEPFAR
6 · The paper itself

Abstract

Adolescent girls and young women (AGYW) in sub-Saharan Africa remain at high risk for HIV, yet limited data exist on implementation of HIV pre-exposure prophylaxis (PrEP) for this group. We examined PrEP uptake among AGYW using a retrospective cohort enrolled in the Determined Resilient Empowered AIDS-free Mentored Safe (DREAMS) initiative in Zambia between October 2020 and March 2022. Consent was obtained from eligible AGYW at substantial risk for HIV, and they voluntarily participated in PrEP. Multivariable logistic regression was used to examine factors associated with PrEP refills following initiation. Of 4,162 HIV-negative AGYW, 3,233 (77%) were at substantial risk and initiated on PrEP. Overall, 68% of AGYW had at least one refill, but this differed significantly by age group and district. DREAMS was successful at reaching AGYW with PrEP services. More evidence is needed to assess reasons for discontinuation and to improve persistence for those with sustained HIV risk.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentFemaleHumansRetrospective StudiesZambiaAnti-HIV AgentsAGYWDREAMSHIV preventionPrEP

Identifiers

PMID37406141
PMCPMC10764235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.