ArticleScience advances2023
Hypoxia sensing requires H
Open access · goldAbstract read
In one paragraph
Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Acute Hypoxia Inhibits KActa physiologica (Oxford, England) · 2026Article
- Multifaceted roles for persulfide species in redox chemical biology.Nature chemical biology · 2026Review
- Heme and CO metabolism by the canonical human heme oxygenases.Journal of inorganic biochemistry · 2026Review
- Intracellular calcium release activates carotid body afferents by fentanyl.Function (Oxford, England) · 2026Article
- Olfactory Decline in Elderly at High Altitudes: A Narrative Review.International journal of general medicine · 2026Review
- Targeting ecto-5'-nucleotidase (CD73) and cAMP alleviates carotid body hyperactivity and reduces blood pressure in chronically hypoxic rats.The Journal of physiology · 2026Article
- Review
- Hydrogen sulfide protects against spinal cord pyroptosis via persulfidation of Rac1 after lumbosacral plexus nerve injury.Cell death discovery · 2025Article
- Activation of the Carotid Body by Kappa Opioid Receptors Mitigates Fentanyl-Induced Respiratory Depression.Function (Oxford, England) · 2025Article
- The Role of Hydrogen Sulfide in the Regulation of the Pulmonary Vasculature in Health and Disease.Antioxidants (Basel, Switzerland) · 2025Review
- Signal Transduction Pathway Mediating Carotid Body Dependent Sympathetic Activation and Hypertension by Chronic Intermittent Hypoxia.Function (Oxford, England) · 2025Article
- Article
- The Application of Hydrogen Sulfide Fluorescent Probe in Food Preservation, Detection and Evaluation.Molecules (Basel, Switzerland) · 2024Review
- Intracellular Allosteric Antagonist of the Olfactory Receptor OR51E2.Molecular pharmacology · 2024Article
- Overexpression of olfactory receptor 78 ameliorates brain injury in cerebral ischaemia-reperfusion rats by activating Prkaca-mediated cAMP/PKA-MAPK pathway.Journal of cellular and molecular medicine · 2024Article
- Article
- Carotid Body Function in Tyrosine Hydroxylase Conditional Olfr78 Knockout Mice.Function (Oxford, England) · 2024Article
- Potential therapeutic effects of traditional Chinese medicine in acute mountain sickness: pathogenesis, mechanisms and future directions.Frontiers in pharmacology · 2024Review
- Exploring the Potential of Olfactory Receptor Circulating RNA Measurement for Preeclampsia Prediction and Its Linkage to Mild Gestational Hypothyroidism.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 2 countries.
Ying-Jie PengInstitute for Integrative Physiology, Biological Sciences Division, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-8302-5198
Jayasri NanduriInstitute for Integrative Physiology, Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Ning WangInstitute for Integrative Physiology, Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Ganesh K KumarInstitute for Integrative Physiology, Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Vytautas BindokasDepartment of Physiology and Pharmacological Sciences, Biological Sciences Division, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-1053-2284
Bindu D PaulDepartment of Pharmacology, The Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-1862-6103
Xuanmao ChenDepartment of Molecular, Cellular and Biomedical Sciences, College of Life Sciences and Agriculture, University of New Hampshire, Durham, NH USA.ORCID 0000-0002-0057-8510
Aaron P FoxDepartment of Physiology and Pharmacological Sciences, Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Thibaut VignaneLeibniz-Institut für Analytische Wissenschaften-ISAS, Bunsen-Kirchhoff-Straße, 1144139 Dortmund, Germany.ORCID 0000-0002-3377-3187
Milos R FilipovicLeibniz-Institut für Analytische Wissenschaften-ISAS, Bunsen-Kirchhoff-Straße, 1144139 Dortmund, Germany.
Nanduri R PrabhakarInstitute for Integrative Physiology, Biological Sciences Division, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4570-1380
University of Chicago · USLeibniz Institute for Analytical Sciences - ISAS · DEUniversity of Illinois Chicago · USJohns Hopkins University · USUniversity of New Hampshire · US
Funding
Mechanisms Underlying Sympathetic Activation-dependent Endothelial Cell Activation by Chronic Intermittent HypoxiaP01HL144454 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2019 to 2023
$12.7MNeuroprotective actions of cystathionine g-lyase through gasotransmitter hydrogen sulfide signalingR01AG071512 · NIA · JOHNS HOPKINS UNIVERSITY · PI Bindu Paul · 2022 to 2026
$3.4McAMP signaling and three activity states of hippocampal neuronsR15MH125305 · NIMH · UNIVERSITY OF NEW HAMPSHIRE · PI CHEN, XUANMAO · 2021 to 2025
$682kNeuronal primary cilia and cognitive disordersR15MH126317 · NIMH · UNIVERSITY OF NEW HAMPSHIRE · PI CHEN, XUANMAO · 2021 to 2021
$452kRole of sulfhydration on the functions of the microtubule associated protein, TauR21AG073684 · NIA · JOHNS HOPKINS UNIVERSITY · PI PAUL, BINDU · 2021 to 2022
$450kThe role of AC3 in neuronal activity and depression-related phenotypeR21MH105746 · NIMH · UNIVERSITY OF WASHINGTON · PI CHEN, XUANMAO · 2015 to 2016
$398kNHLBI NIH HHS P01 HL144454NIA NIH HHS R01 AG071512NIA NIH HHS R21 AG073684NIMH NIH HHS R15 MH125305NIMH NIH HHS R15 MH126317NIMH NIH HHS R21 MH105746
Abstract
Oxygen (O
Indexed as
Carotid BodyHydrogen SulfideReceptors, OdorantHumansHypoxiaOxygenHydrogen SulfideOxygenReceptors, Odorant
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.