Evidence map›Paper›PMID 37405518›Full record

ArticleDiscover oncology2023

The tumor-stroma ratio and the immune microenvironment improve the prognostic prediction of pancreatic ductal adenocarcinoma.

Mei Lu, Yi Zou, Peiling Fu, Yuyang Li, Pengcheng Wang, Guoping Li, Sheng Luo, Yupeng Chen, Guoping Guan, Sheng Zhang and 1 more

Abstract read
In one paragraph

Article in Discover oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mei Lu *Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Yi Zou *Department of Pathology, Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Peiling FuDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Yuyang LiDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Pengcheng WangDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Guoping LiDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Sheng LuoDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Yupeng ChenDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Guoping GuanFuqing City Hospital Affiliated to Fujian Medical University, Fuqing, Fujian, China.
Sheng ZhangDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China.
Linying ChenDepartment of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China. chenly2006@126.com.

Funding

Fujian Key Laboratory of Translational Research in Cancer and Neurodegenerative Diseases FKLTR-202101the 2020 Fujian Provincial Health Science and Technology Project for Youth Research Project 2020QNA041the Joint Funds for the Innovation of Science and Technology, Fujian Province 2021Y9145the Scientific Research Project of National Key Clinical Specialty Construction Project 2022YBL-ZD-05
6 · The paper itself

Abstract

Tumor-infiltrating immune cells and fibroblasts are significant components of the tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC), and they participate in tumor progression as closely as tumor cells. However, the relationship between the features of the TME and patient outcomes and the interactions among TME components are still unclear. In this study, we evaluated the PDAC TME in terms of the quantity and location of cluster of differentiation (CD)4

Indexed as

Pancreatic ductal adenocarcinomaPrognosisTumor microenvironmentTumor–node–metastasis stagingTumor–stroma ratio

Identifiers

PMID37405518
PMCPMC10322806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.