Evidence map›Paper›PMID 37405394›Full record

ArticleMicrobial genomics2023

Long-read sequencing reveals genomic diversity and associated plasmid movement of carbapenemase-producing bacteria in a UK hospital over 6 years.

Leah W Roberts, David A Enoch, Fahad Khokhar, Grace A Blackwell, Hayley Wilson, Ben Warne, Theodore Gouliouris, Zamin Iqbal, M Estée Török

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Plasmid genomic epidemiology ofMicrobial genomics · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Utility of hybrid whole genome sequencing in assessing potential nosocomial VIM transmission.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Leah W RobertsEuropean Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, UK.
David A EnochClinical Microbiology & Public Health Laboratory, UK Health Security Agency, Cambridge, UK.
Fahad KhokharCentre for Therapeutic Immunology and Infectious Diseases, University of Cambridge, Cambridge, UK.
Grace A BlackwellSanger Institute, Wellcome Genome Campus, Hinxton, UK.
Hayley WilsonDepartment of Medicine, University of Cambridge, England, UK.
Ben WarneDepartment of Medicine, University of Cambridge, England, UK.
Theodore GouliourisDepartment of Medicine, University of Cambridge, England, UK.
Zamin IqbalEuropean Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, UK.
M Estée TörökDepartment of Medicine, University of Cambridge, England, UK.
University of Cambridge · GBEuropean Bioinformatics Institute · GBUK Health Security Agency · GBWellcome Sanger Institute · GB

Funding

Department of Health
6 · The paper itself

Abstract

Healthcare-associated infections (HCAIs) affect the most vulnerable people in society and are increasingly difficult to treat in the face of mounting antimicrobial resistance (AMR). Routine surveillance represents an effective way of understanding the circulation and burden of bacterial resistance and transmission in hospital settings. Here, we used whole-genome sequencing (WGS) to retrospectively analyse carbapenemase-producing Gram-negative bacteria from a single hospital in the UK over 6 years (

Indexed as

HospitalsKlebsiella pneumoniaeBacterial Proteinsbeta-LactamasesEscherichia coliGenomicsHumansPlasmidsRetrospective StudiesUnited KingdomBacterial Proteinsbeta-Lactamasescarbapenemasecarbapenemaselong-read sequencingplasmidST78transmissionwhole genome sequencing

Identifiers

PMID37405394
PMCPMC10438816
OpenAlexW4383186289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.