Evidence map›Paper›PMID 37405371›Full record

ArticleAutophagy2024

Autophagy is required for stem-cell-mediated endometrial programming and the establishment of pregnancy.

Pooja Popli, Ramakrishna Kommagani

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pooja PopliDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.
Ramakrishna KommaganiDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · US

Funding

MOLECULAR AND METABOLIC ASPECTS OF IMPLANTATIONR01HD065435 · NICHD · WASHINGTON UNIVERSITY · PI KOMMAGANI, RAMAKRISHNA, SANTI, CELIA M · 2010 to 2020
$4.5M
ROLE OF THE GUT MICROBIOTA IN ENDOMETRIOSISR01HD102680 · NICHD · WASHINGTON UNIVERSITY · PI Ramakrishna Kommagani · 2021 to 2026
$2.4M
Post-Transcriptional Regulation of Embryo ImplantationR01HD104813 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Ramakrishna Kommagani · 2022 to 2026
$2.1M
NICHD NIH HHS R01 HD065435NICHD NIH HHS R01 HD102680NICHD NIH HHS R01 HD104813
6 · The paper itself

Abstract

Autophagy plays an important role in the normal growth and morphogenesis of a variety of tissues. Its role in uterine maturation, however, is not fully characterized. Recently, we reported that BECN1 (Beclin1)-dependent autophagy, but not apoptosis, is crucial for stem cell-mediated endometrial programming and the establishment of pregnancy in mice. Upon genetic and pharmacological inhibition of BECN1-mediated autophagy, female mice displayed severe endometrial structural and functional defects leading to infertility. Specifically, conditional loss of

Indexed as

AutophagyEndometriumStem CellsAnimalsApoptosisBeclin-1FemaleMicePregnancyUterusBeclin-1apoptosisAutophagybeclin-1endocytosisendometriummorphogenesisstem cells

Identifiers

PMID37405371
PMCPMC11062356
OpenAlexW4383186762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.