Evidence map›Paper›PMID 37405211›Full record

ArticleCancer diagnosis & prognosis

Interobserver Variability in Contouring Hepatocellular Carcinoma at a Tertiary Center.

Carolina DE LA Pinta, Juan David García, David Sevillano, Rafael Colmenares, Raquel García Latorre, Manuel Garví, Vanesa Pino, Alfonso Muriel, Mercedes Martín, Eva Fernández and 7 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Carolina DE LA PintaRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Juan David GarcíaMedical Physics Department, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
David SevillanoMedical Physics Department, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
Rafael ColmenaresMedical Physics Department, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
Raquel García LatorreRadiology Department, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
Manuel GarvíRadiation therapist, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
Vanesa PinoRadiation therapist, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
Alfonso MurielClinical Βiostatistics Unit, Ramón y Cajal University Hospital, IRYCIS, CIBERESP, Universidad de Alcalá, Madrid, Spain.
Mercedes MartínRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Eva FernándezRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Raul HernanzRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Margarita MartínRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Jose Antonio DomínguezRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Teresa MuñózRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Luis Cristian PernaPathology Department, Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain.
Agustín AlbillosDepartment of Gastroenterology, Ramón y Cajal University Hospital, Universidad de Alcalá, IRYCIS, CIBEREHD, Madrid, Spain.
Sonsoles SanchoRadiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain.
Instituto Cajal · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESUniversidad de Alcalá · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe optimal imaging test for delineation of the gross tumor volume (GTV) in hepatocellular carcinoma has not been defined. The hypothesis is that magnetic resonance imaging (MRI) allows for better visualization of the extent of tumor and will optimize the accuracy of tumor delineation for liver stereotactic radiotherapy compared with computed tomography (CT) only. We evaluated the interobserver agreement in GTV of hepatocellular carcinoma in a multicenter panel and compared MRI and CT in GTV delineation. MATERIALS AND

methodsAfter the institutional review boards approved the study, we analyzed anonymous CT and MRI obtained from five patients with hepatocellular carcinoma. Eight radiation oncologists at our center used CT and MRI to delineate five GTVs of liver tumors. In both CT and MRI, the GTV volumes were compared.

resultsThe median GTV volume on MRI was 2.4 cm

conclusionIn cases with well-defined tumors, CT is easier and reproducible. In cases with no defined tumor in CT, other tools are needed and MRI can be complementary. The interobserver variability in target delineation of hepatocellular carcinoma in this study is noteworthy.

Indexed as

Contouringhepatocellular carcinomaliverSBRTsegmentationvariability

Identifiers

PMID37405211
PMCPMC10316061
OpenAlexW4382986071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.