Evidence map›Paper›PMID 37405207›Full record

ArticleChemistry of materials : a publication of the American Chemical Society2016

Luteinizing Hormone Releasing Hormone-Targeted Cisplatin-Loaded Magnetite Nanoclusters for Simultaneous MR Imaging and Chemotherapy of Ovarian Cancer.

Hemant M Vishwasrao, Alyssa M Master, Youn Gee Seo, Xinming M Liu, Nikorn Pothayee, Zhengyuan Zhou, Dongfen Yuan, Michael D Boska, Tatiana K Bronich, Richey M Davis and 3 more

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry of materials : a publication of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Hemant M VishwasraoCenter for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Alyssa M MasterCenter for Nanotechnology in Drug Delivery, Molecular Pharmaceutics Division, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Youn Gee SeoCenter for Nanotechnology in Drug Delivery, Molecular Pharmaceutics Division, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Xinming M LiuCenter for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Nikorn PothayeeLaboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, United States.
Zhengyuan ZhouCenter for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Dongfen YuanCenter for Nanotechnology in Drug Delivery, Molecular Pharmaceutics Division, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Michael D BoskaDepartment of Radiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Tatiana K BronichCenter for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Richey M DavisMacromolecules and Interfaces Institute, Virginia Tech, Blacksburg, Virginia 24061, United States.
Judy S RiffleMacromolecules and Interfaces Institute, Virginia Tech, Blacksburg, Virginia 24061, United States.
Marina Sokolsky-PapkovCenter for Nanotechnology in Drug Delivery, Molecular Pharmaceutics Division, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Alexander V KabanovCenter for Nanotechnology in Drug Delivery, Molecular Pharmaceutics Division, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
University of North Carolina at Chapel Hill · USUniversity of Nebraska Medical Center · USInterface (United States) · USNational Institutes of Health · USNebraska Medical Center · USVirginia Tech · US

Funding

Targeted Core Shell Nanogels for Triple Negative Breast CancerU01CA198910 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRONICH, TATIANA K, KABANOV, ALEXANDER V · 2015 to 2019
$2.8M
NCI NIH HHS U01 CA198910
6 · The paper itself

Abstract

Given the superior soft tissue contrasts obtained by MRI and the long residence times of magnetic nanoparticles (MNPs) in soft tissues, MNP-based theranostic systems are being developed for simultaneous imaging and treatment. However, development of such theranostic nanoformulations presents significant challenges of balancing the therapeutic and diagnostic functionalities in order to achieve optimum effect from both. Here we developed a simple theranostic nanoformulation based on magnetic nanoclusters (MNCs) stabilized by a bisphosphonate-modified poly(glutamic acid)-

Identifiers

PMID37405207
PMCPMC10317193
OpenAlexW2345353327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.