Evidence map›Paper›PMID 37405169›Full record

ArticleFrontiers in microbiology2023

Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system.

Victoria Røyseth, Brianna M Hurysz, Anna-Karina Kaczorowska, Sebastian Dorawa, Anita-Elin Fedøy, Hasan Arsın, Mateus Sá M Serafim, Samuel A Myers, Olesia Werbowy, Tadeusz Kaczorowski and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Victoria RøysethDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Brianna M HuryszSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, San Diego, CA, United States.
Anna-Karina KaczorowskaCollection of Plasmids and Microorganisms | KPD, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Sebastian DorawaLaboratory of Extremophiles Biology, Department of Microbiology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Anita-Elin FedøyDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Hasan ArsınDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Mateus Sá M SerafimSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, San Diego, CA, United States.
Samuel A MyersLa Jolla Institute for Immunology, La Jolla, CA, United States.
Olesia WerbowyLaboratory of Extremophiles Biology, Department of Microbiology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Tadeusz KaczorowskiLaboratory of Extremophiles Biology, Department of Microbiology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Runar StokkeDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Anthony J O'DonoghueSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, San Diego, CA, United States.
Ida Helene SteenDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
University of Bergen · NOUniversity of Gdańsk · PLUniversity of California San Diego · USLa Jolla Institute for Immunology · USUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep-sea hydrothermal vents offer unique habitats for heat tolerant enzymes with potential new enzymatic properties. Here, we present the novel C11 protease

Indexed as

clostripaincysteine peptidaseextracellular enzymehydrothermal ventmetagenome bioprospecting

Identifiers

PMID37405169
PMCPMC10315481
OpenAlexW4381166523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.