Evidence map›Paper›PMID 37405123›Full record

ArticleCancer research communications2023

Targeting the Clear Cell Sarcoma Oncogenic Driver Fusion Gene

Hirokazu Mae, Hidetatsu Outani, Yoshinori Imura, Ryota Chijimatsu, Akitomo Inoue, Yuki Kotani, Naohiro Yasuda, Sho Nakai, Takaaki Nakai, Satoshi Takenaka and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer research communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. International journal of molecular sciences · 2024
    Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hirokazu MaeDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0009-0000-4617-0409
Hidetatsu OutaniDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-5407-5855
Yoshinori ImuraDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-0430-5894
Ryota ChijimatsuCenter for Comprehensive Genomic Medicine, Okayama University Hospital, Okayama, Japan.ORCID 0000-0002-3125-4818
Akitomo InoueDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0009-0007-3524-491X
Yuki KotaniDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0001-7157-4560
Naohiro YasudaDepartment of Orthopedic Surgery, Osaka National Hospital, Osaka, Japan.ORCID 0000-0001-9631-0668
Sho NakaiMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka, Japan.ORCID 0000-0001-9230-0817
Takaaki NakaiDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-4083-6123
Satoshi TakenakaMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka, Japan.ORCID 0000-0002-4796-5817
Seiji OkadaDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-5107-8209
Osaka City University · JPOsaka International Cancer Institute · JPOkayama University Hospital · JPOsaka National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell sarcoma (CCS), a rare but extremely aggressive malignancy with no effective therapy, is characterized by the expression of the oncogenic driver fusion gene Significance: This study reveals the epigenetic and transcriptional suppression mechanism of the fusion oncogene

Indexed as

Sarcoma, Clear CellTranscription FactorsBromodomain Containing ProteinsCell Cycle ProteinsHistone Deacetylase InhibitorsHumansNuclear ProteinsRNA-Binding Protein EWSVorinostatBRD4 protein, humanBromodomain Containing ProteinsCell Cycle ProteinsEWSR1 protein, humanHistone Deacetylase InhibitorsNuclear ProteinsRNA-Binding Protein EWSTranscription FactorsVorinostat

Identifiers

PMID37405123
PMCPMC10317042
OpenAlexW4380049614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.