ReviewWorld journal of gastrointestinal surgery2023
Median arcuate ligament syndrome often poses a diagnostic challenge: A literature review with a scope of our own experience.
Review in World journal of gastrointestinal surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Outcomes of surgical versus conservative treatment in pediatric median arcuate ligament syndrome.Journal of pediatric gastroenterology and nutrition · 2026Article
- Collateral circulation as a possible predictor of symptomatic median arcuate ligament syndrome: a case report.Annals of medicine and surgery (2012) · 2026Article
- Laparoscopic Approach to Median Arcuate Ligament Syndrome: A Single-Center Experience.Medicina (Kaunas, Lithuania) · 2026Observational
- The Coexistence of Median Arcuate Ligament Syndrome and Gastric Cancer.ACG case reports journal · 2025Article
- Median arcuate ligament syndrome (MALS): A case report of a young patient.International journal of surgery case reports · 2025Article
- Laparoscopic median arcuate ligament release with an antegrade approach in adolescents and young adults: a single center experience.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Laparoscopic median arcuate ligament release using an anterior approach for median arcuate ligament syndrome.Annals of gastroenterological surgery · 2024Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The median arcuate ligament syndrome (MALS) is recognized as a rare clinical entity, characterized by chronic post-prandial abdominal pain, nausea, vomiting, and unintentional weight loss. Due to its vague symptomatology, it is mainly regarded as a diagnosis of exclusion. Patients can often be misdiagnosed for several years before a correct diagnosis is established, also due to a medical team's clinical suspicion. We present a case series of two patients who suffered from MALS and were treated successfully. The first patient is a 32-year-old woman, presenting with post-prandial abdominal pain and weight loss that have lasted for the past ten years. The second patient, a 50-year-old woman, presented with similar symptomatology, with the symptoms lasting for the last five years. Both cases were treated by laparoscopic division of the median arcuate ligament fibers, which alleviated extrinsic pressure from the celiac artery. Previous cases of MALS were retrieved from PubMed, to assemble a better diagnostic algorithm and propose a treatment method of choice. The literature review suggests an angiography with a respiratory variation protocol as the diagnostic modality of choice, along with the laparoscopic division of the median arcuate ligament fibers as the proposed treatment of choice.
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Registered trials
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