Evidence map›Paper›PMID 37405041›Full record

ArticleClinical case reports2023

A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow-derived stem cells.

Rita T Boulos, Lea I Nemer, Vanessa J Mansour, Cynthia F Najjoum, Elsa A Asmar, Nassim H Abi Chahine

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Rita T BoulosStem Cell Transplantation/Neurology ACE Cells Lab Limited Beirut Lebanon.
Lea I NemerStem Cell Transplantation/Molecular Biology ACE Cells Lab Limited Beirut Lebanon.ORCID https://orcid.org/0000-0002-8105-7556
Vanessa J MansourStem Cell Transplantation/Infectious Diseases/Immunology ACE Cells Lab Limited Beirut Lebanon.
Cynthia F NajjoumStem Cell Transplantation/Infectious Diseases/Immunology ACE Cells Lab Limited Beirut Lebanon.
Elsa A AsmarStem Cell Transplantation/Functional Genomics/Proteomics ACE Cells Lab Limited Beirut Lebanon.
Nassim H Abi ChahineStem Cell Transplantation/Neurological Surgery ACE Cells Lab Limited Beirut Lebanon.
Cells Therapy (Poland) · PLAutomated Cells & Equipment (United States) · USCell Medica (Switzerland) · CHShanghai Cell Therapy Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: Promising outcomes are shown in this case report using the Regentime procedure and autologous stem cells to treat spinal cord injury. The observed "First Show Phenomenon" provides valuable insights into the therapy's potential for spinal cord injury. Abstract: This case report demonstrates "the first show phenomenon" following Regentime stem cell therapy applied to a spinal cord injury patient. A 40-year-old gentleman sustained a ballistic injury at the level of T9, resulting in complete bilateral motor and sensory loss from T9 and below. He was treated with autologous bone marrow-derived mononuclear stem cells injected into his spinal canal 2.5 years after his injury. Follow-up during the first-week posttransplantation showed early symptom improvement termed "the first show phenomenon." He regained sensation to light touch in his lower limbs by the end of week 1 and reported no serious implications or complications.

Indexed as

autologous bone marrow‐derived mononuclear stem cellsfirst show phenomenonRegentime therapyspinal cord injurystem cell therapy

Identifiers

PMID37405041
PMCPMC10315442
OpenAlexW4382927770

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.