ArticleMissouri medicine
Novel Hematological Biomarker Adopted for Early Sepsis Detection Emerges as Predictor of Severity for COVID Infection.
Article in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The Role of Monocyte Distribution Width (MDW) in the Prediction of Death in Adult Patients with Sepsis.Microorganisms · 2025Article
- The Need for Standardized Guidelines for the Use of Monocyte Distribution Width (MDW) in the Early Diagnosis of Sepsis.Journal of personalized medicine · 2024Review
- Inflammatory markers as outcome predictors of COVID-19 in pregnant women.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Monocyte Distribution Width (MDW) as a useful and cost-effective biomarker for sepsis prediction.Journal of circulating biomarkersArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sepsis is a major health care burden with significant contribution to morbidity, mortality, and hospital resource utilization. Monocyte Distribution Width (MDW), the novel hematological biomarker, was clinically implemented in our laboratory for early detection of sepsis (ESId) in 2019. When COVID-19 pandemic hit in 2020, we noticed some similarities of the laboratory data of the COVID patients with patients previously diagnosed with sepsis. The aim of this study was to evaluate the value of the hematological data including MDW in predicting COVID disease severity and outcome. A retrospective study was conducted on 130 COVID-infected patients who presented at our hospital during March and April 2020. Collected data included clinical, laboratory, and radiological findings. This study demonstrates a unique pattern of three hematological biomarkers that predicted severity and outcome in COVID patients at their initial presentation in the Emergency Room (ER): higher absolute neutrophil count (ANC), lower absolute lymphocyte count (ALC), and higher MDW.
Indexed as
Identifiers
37404879PMC10317102What OpenQuestion holds
Registered trials
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