ReviewFrontiers in veterinary science2023
Alternatives to antibiotics for treatment of mastitis in dairy cows.
Review in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 65 citations in OpenAlex.
- Effects of bovine lactoferrin on the growth and biofilm formation of Escherichia coli and Klebsiella pneumoniae associated with bovine mastitis.Veterinary research communications · 2026Article
- Genomic Characterization of Multidrug-ResistantMicroorganisms · 2026Article
- Protective effect of snail secretion filtrate in an in vitro model of mastitis.Veterinary record open · 2026Article
- Integrated methylome-transcriptome profiling reveals epigenetic regulation of immune activation pathways and CSN3-associated lactation repression in bovine subclinical mastitis.Journal of animal science and biotechnology · 2026Article
- Palo Santo (Bursera graveolens) essential oil nanoemulsion: toxicological, antinociceptive and antimicrobial potential against bovine mastitis-associated strains.Antonie van Leeuwenhoek · 2026Article
- Development of long-term antimicrobial resistance patterns of bovine mastitis pathogens in north-western Germany from 2005 to 2023.Veterinary research communications · 2026Article
- Exploring the Therapeutic Potential of Essential Oils of the Valdivian Rainforest (Animals : an open access journal from MDPI · 2026Article
- Bovine Mastitis Therapy at a Crossroads: Pharmacokinetic Barriers, Biofilms, Antimicrobial Resistance, and Emerging Solutions.Pharmaceuticals (Basel, Switzerland) · 2026Review
- One Health Perspective on Antimicrobial Resistance in Bovine Mastitis Pathogens-A Narrative Review.Antibiotics (Basel, Switzerland) · 2026Review
- Synergistic antibacterial effect of CATH-2 and D-amino acids against mastitis causing gram-positive bacteria.Frontiers in cellular and infection microbiology · 2026Article
- Evaluation of tri-plate rapid on-farm culture system to make therapeutic decisions for mastitis cases in dairy cattle.PloS one · 2026Article
- Ferroptosis in bovine mastitis: multidimensional mechanisms, stratified assessment, and intervention prospects.Frontiers in veterinary science · 2026Review
- Nonantibiotic Alternatives for Mastitis in Small Ruminants: A Scoping Review of Evidence, Gaps, and Translational Challenges.Veterinary medicine international · 2026Review
- Subclinical mastitis of buffaloes in Asia: prevalence, pathogenesis, risk factors, antimicrobial resistance, and current treatment strategies.Journal of animal science and technology · 2026Review
- Combating bovine mastitis: current insights and future directions for a global dairy challenge.Archives animal breeding · 2026Review
- The effect of staphylococcal infection on cathelicidin and β-defensin mRNA levels in epithelial cells lining the mammary gland cistern.Frontiers in immunology · 2026Article
- Antibiotic Residues in Milk as a Consequence of Mastitis Treatment: Balancing Animal Welfare and One Health Risks.Veterinary sciences · 2025Review
- The future of udder health: Antimicrobial stewardship and alternative therapy of bovine mastitis.JDS communications · 2025Review
- Genomic and In Vitro Analysis of Pediococcus pentosaceus MBBL4 Implicated Its Therapeutic Use Against Mastitis Pathogens and as a Potential Probiotic.Probiotics and antimicrobial proteins · 2025Article
- In vitro antimicrobial activity of polyhexamethylene guanidine hydrochloride and polyhexamethylene biguanide against microorganisms causing bovine mastitis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mastitis is considered the costliest disease on dairy farms and also adversely affects animal welfare. As treatment (and to a lesser extent prevention) of mastitis rely heavily on antibiotics, there are increasing concerns in veterinary and human medicine regarding development of antimicrobial resistance. Furthermore, with genes conferring resistance being capable of transfer to heterologous strains, reducing resistance in strains of animal origin should have positive impacts on humans. This article briefly reviews potential roles of non-steroidal anti-inflammatory drugs (NSAIDs), herbal medicines, antimicrobial peptides (AMPs), bacteriophages and their lytic enzymes, vaccination and other emerging therapies for prevention and treatment of mastitis in dairy cows. Although many of these approaches currently lack proven therapeutic efficacy, at least some may gradually replace antibiotics, especially as drug-resistant bacteria are proliferating globally.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.