Evidence map›Paper›PMID 37404434›Full record

ArticleCureus2023

Clinicopathological Profile of a Cohort of Patients With Malignant Melanoma in the United Kingdom.

Saroona Haroon, Iresha Vithanage, Khushbakht Rashid, Mahnoor Aslam, Heba Elmahdy, Shamail Zia, Umair Arshad Malik, Muhammad Irfan, Atif A Hashmi

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Saroona HaroonPathology, King's Mill Hospital, Sutton-in-Ashfield, GBR.
Iresha VithanagePathology, King's Mill Hospital, Sutton-in-Ashfield, GBR.
Khushbakht RashidInternal Medicine, Liaquat National Hospital and Medical College, Karachi, PAK.
Mahnoor AslamInternal Medicine, Baqai Medical University, Karachi, PAK.
Heba ElmahdyDermatology, King's Mill Hospital, Sutton-in-Ashfield, GBR.
Shamail ZiaPathology, Jinnah Sindh Medical University, Karachi, PAK.
Umair Arshad MalikInternal Medicine, Aga Khan University, Karachi, PAK.
Muhammad IrfanStatistics, Liaquat National Hospital and Medical College, Karachi, PAK.
Atif A HashmiPathology, Liaquat National Hospital and Medical College, Karachi, PAK.
Baqai Medical University · PKKings Mill Hospital · GBLiaquat National Hospital · PKAga Khan University · PKUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Malignant melanoma (MM) is potentially a fatal type of skin cancer and a major health concern for the Caucasian population. It is a heterogeneous disease with a wide spectrum of manifestations. Therefore, in this study, we evaluated the clinicopathological characteristics of MM. Methods We retrospectively studied the clinicopathological characteristics of MM in 167 biopsy-proven cases of MM reported between January 2020 and December 2021 at Kings Mill Hospital, Sutton-in-Ashfield, United Kingdom. Clinical data such as the age, sex, and anatomical site of the lesion were obtained from the clinical referral forms. Biopsies of the lesions were performed, and the specimens collected were sent to the laboratory for histopathological study and v-raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation evaluation. Formalin-fixed paraffin-embedded blocks (FFPE) were prepared, sectioned, and stained with hematoxylin and eosin for histological examination. Results A total of 167 cases of MM were included in the study. The age range was 23-96 years, with the median age at diagnosis found to be 66 years; males were more commonly affected (52.1%). The median Breslow thickness was 1.20 mm. The median mitotic activity was 1.0/mm

Indexed as

breslow thicknessclarks levelclinicopathological profilemalignant melanomanodular melanoma

Identifiers

PMID37404434
PMCPMC10315104
OpenAlexW4379141878

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.