Evidence map›Paper›PMID 37404336›Full record

ArticleFrontiers in neuroinformatics2023

Enhancing collaborative neuroimaging research: introducing COINSTAC Vaults for federated analysis and reproducibility.

Dylan Martin, Sunitha Basodi, Sandeep Panta, Kelly Rootes-Murdy, Paul Prae, Anand D Sarwate, Ross Kelly, Javier Romero, Bradley T Baker, Harshvardhan Gazula and 6 more

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Dylan MartinTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Sunitha BasodiTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Sandeep PantaTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Kelly Rootes-MurdyTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Paul PraeTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Anand D SarwateTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Ross KellyTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Javier RomeroTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Bradley T BakerTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Harshvardhan GazulaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Jeremy BockholtTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Jessica A TurnerTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Nathalia B EsperCenter for the Developing Brain, Child Mind Institute, New York, NY, United States.
Alexandre R FrancoCenter for the Developing Brain, Child Mind Institute, New York, NY, United States.
Sergey PlisTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.
Vince D CalhounTri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta, GA, United States.

Funding

COINSTAC: Decentralized, Scalable Analysis of Loosely Coupled DataR01DA040487 · NIDA · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D, PLIS, SERGEY · 2015 to 2024
$7.1M
ENIGMA-COINSTAC-APOE2 Functional and structural connectome protective mechanisms for Alzheimer’s disease and mood disorders: Request for supplemental funds for NIH R01:1R01MH121246R01MH121246 · NIMH · OHIO STATE UNIVERSITY · PI CALHOUN, VINCE D, TURNER, JESS · 2019 to 2023
$5.0M
A decentralized macro and micro gene-by-environment interaction analysis of substance use behavior and its brain biomarkers R01DA049238 · NIDA · GEORGIA STATE UNIVERSITY · PI CALHOUN, VINCE D, LIU, JINGYU · 2019 to 2023
$2.9M
NIDA NIH HHS R01 DA040487NIDA NIH HHS R01 DA049238NIMH NIH HHS R01 MH121246
6 · The paper itself

Abstract

Collaborative neuroimaging research is often hindered by technological, policy, administrative, and methodological barriers, despite the abundance of available data. COINSTAC (The Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymous Computation) is a platform that successfully tackles these challenges through federated analysis, allowing researchers to analyze datasets without publicly sharing their data. This paper presents a significant enhancement to the COINSTAC platform: COINSTAC Vaults (CVs). CVs are designed to further reduce barriers by hosting standardized, persistent, and highly-available datasets, while seamlessly integrating with COINSTAC's federated analysis capabilities. CVs offer a user-friendly interface for self-service analysis, streamlining collaboration, and eliminating the need for manual coordination with data owners. Importantly, CVs can also be used in conjunction with open data as well, by simply creating a CV hosting the open data one would like to include in the analysis, thus filling an important gap in the data sharing ecosystem. We demonstrate the impact of CVs through several functional and structural neuroimaging studies utilizing federated analysis showcasing their potential to improve the reproducibility of research and increase sample sizes in neuroimaging studies.

Indexed as

COINSTACcollaborative analysisdatasetsfederated learningneuroimagingopen scienceprivacyreproducibility

Identifiers

PMID37404336
PMCPMC10315678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.