Evidence map›Paper›PMID 37404190›Full record

ArticleApplied and environmental microbiology2023

Horizontal Gene Transfer and CRISPR Targeting Drive Phage-Bacterial Host Interactions and Coevolution in "Pink Berry" Marine Microbial Aggregates.

James C Kosmopoulos, Danielle E Campbell, Rachel J Whitaker, Elizabeth G Wilbanks

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Applied and environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Treatment ofViruses · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Targeted hypermutation of putative antigen sensors in multicellular bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James C Kosmopoulos *Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Danielle E Campbell *Microbial Diversity 2020, University of Chicago Marine Biological Laboratory, Falmouth, Massachusetts, USA.ORCID 0000-0002-4072-3874
Rachel J WhitakerMicrobial Diversity 2020, University of Chicago Marine Biological Laboratory, Falmouth, Massachusetts, USA.
Elizabeth G WilbanksMicrobial Diversity 2020, University of Chicago Marine Biological Laboratory, Falmouth, Massachusetts, USA.
Marine Biological Laboratory · US

Funding

Pediatric Gastroenterology Research Training ProgramT32DK077653 · NIDDK · WASHINGTON UNIVERSITY · PI PHILLIP I TARR · 2007 to 2026
$5.8M
HHS | National Institutes of Health (NIH) T32 DK077653-29NIDDK NIH HHS T32 DK077653
6 · The paper itself

Abstract

Bacteriophages (phages), which are viruses that infect bacteria, are the most abundant components of microbial communities and play roles in community dynamics and host evolution. However, the study of phage-host interactions is hindered by a paucity of model systems from natural environments. Here, we investigate phage-host interactions in the "pink berry" consortia, which are naturally occurring, low-diversity, macroscopic bacterial aggregates that are found in the Sippewissett Salt Marsh (Falmouth, MA, USA). We leverage metagenomic sequence data and a comparative genomics approach to identify eight compete phage genomes, infer their bacterial hosts from host-encoded clustered regularly interspaced short palindromic repeats (CRISPRs), and observe the potential evolutionary consequences of these interactions. Seven of the eight phages identified infect known pink berry symbionts, namely,

Indexed as

BacteriophagesClustered Regularly Interspaced Short Palindromic RepeatsFruitGene Transfer, HorizontalHost Microbial InteractionsHumansCRISPRhorizontal gene transfermetagenomicsmicrobial ecologymicrobial evolutionphageviromics

Identifiers

PMID37404190
PMCPMC10370329
OpenAlexW4383186927

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.