Trial reportRadiology2023
Generating High-Resolution Synthetic CT from Lung MRI with Ultrashort Echo Times: Initial Evaluation in Cystic Fibrosis.
Open access · greenAbstract readClinical TrialMulticenter Study
In one paragraph
Trial report in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Non-contrast enhanced functional lung MRI in children: systematic review.Frontiers in pediatrics · 2025Pooled it
- RadiolGAN: Multicenter Feasibility Study of Synthetic CT From 3D Ultra-Short Echo Time MRI for Enhanced Pulmonary Radiologic Sign Visualization.Journal of magnetic resonance imaging : JMRI · 2026Article
- Editorial for "RadiolGAN: Multicenter Feasibility Study of Synthetic CT From 3D Ultra-Short Echo Time MRI for Enhanced Pulmonary Radiologic Sign Visualization".Journal of magnetic resonance imaging : JMRI · 2026Article
- Characterizing chronic obstructive pulmonary disease using quantitative MRI biomarkers.The British journal of radiology · 2026Review
- Comprehensive evaluation of a deep learning-based synthetic CT model for MR-only radiotherapy across multiple anatomical sites.Physics and imaging in radiation oncology · 2026Article
- Pleuropulmonary blastoma and the challenge of distinguishing the cystic form (type I) from other congenital lung malformations.Pediatric radiology · 2026Review
- Diagnostic accuracy of ultrashort echo times-MRI in patients with and without idiopathic pulmonary fibrosis.European radiology · 2026Article
- 3D Automated Segmentation of Bronchial Abnormalities on Ultrashort Echo Time MRI: A Quantitative MR Outcome in Cystic Fibrosis.Journal of magnetic resonance imaging : JMRI · 2026Article
- Pulmonary surveillance in inborn errors of immunity: current challenges and emerging approaches.Frontiers in immunology · 2026Review
- Knowledge-based deep residual U-Net (DRU) for synthetic CT generation using a single MR volume for frameless radiosurgery.Journal of applied clinical medical physics · 2026Article
- Gradient system characterization of a 1.5 T MR-Linac with application to 4D UTE imaging for adaptive MR-guided radiotherapy of lung cancer.Magnetic resonance in medicine · 2025Article
- Deep learning applications for quantitative and qualitative PET in PET/MR: technical and clinical unmet needs.Magma (New York, N.Y.) · 2024Review
- Evolving and Novel Applications of Artificial Intelligence in Thoracic Imaging.Diagnostics (Basel, Switzerland) · 2024Review
- Generation of virtual monoenergetic images at 40 keV of the upper abdomen and image quality evaluation based on generative adversarial networks.BMC medical imaging · 2024Article
- Clinical applications of generative artificial intelligence in radiology: image translation, synthesis, and text generation.BJR artificial intelligence · 2024Review
- [Magnetic resonance imaging of the lung : State of the art].Radiologie (Heidelberg, Germany) · 2023Article
- Synthetic Images Are Here to Stay.Radiology · 2023Article
Corrections and comments
- Commented on by
Authors and funding
16 authors at 1 institution in 2 countries.
Arthur LonguefosseFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0009-0009-0261-9812
Julien RaoultFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0009-0007-9927-8166
Ilyes BenlalaFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0002-5953-9882
Baudouin Denis de SennevilleFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0001-5284-8474
Thomas BenkertFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0002-3794-5580
Julie MaceyFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0001-6961-7170
Stéphanie BuiFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0003-3576-2518
Patrick BergerFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0003-4702-0343
Gilbert FerrettiFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0002-5367-7109
Jean-Yves GaubertFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0001-6608-9982
Renan LibergeFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0001-7445-3123
Antoine HuttFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).
Baptiste MorelFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).
François LaurentFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0001-5505-2340
Fabien BaldacciFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0003-4888-4880
Gaël DournesFrom the Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, CIC 1401, Université Bordeaux Segalen, LaBRI, Mathematical Institute of Bordeaux (IMB), 146 rue Léo Saignat, 33076 Bordeaux, France (A.L., I.B., B.D.d.S., P.B., F.L., F.B., G.D.); CNRS, Bordeaux INP, LaBRI, UMR 5800, Bordeaux INP, UMR 5251, Talence, France (A.L., B.D.d.S., F.B.); CHU de Bordeaux, Service d'Imagerie Cardiovasculaire et Thoracique, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, Centre de référence pédiatrique de la mucoviscidose, CIC 1401, Pessac, France (J.R., I.B., J.M., S.B., P.B., F.L., G.D.); INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France (I.B., P.B., F.L., G.D.); MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany (T.B.); Department of Radiology, Grenoble-Alpes University Hospital, Grenoble, France (G.F.); Imaging Department, Hôpital La Timone, APHM, Aix Marseille University, Marseille, France (J.Y.G.); Department of Radiology, CHU Nantes, Nantes, France (R.L.); Department of Thoracic Imaging, Heart & Lung Institute, Lille, France (A.H.); and Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France (B.M.).ORCID 0000-0002-0251-6639
Centre National de la Recherche Scientifique · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Lung MRI with ultrashort echo times (UTEs) enables high-resolution and radiation-free morphologic imaging; however, its image quality is still lower than that of CT. Purpose To assess the image quality and clinical applicability of synthetic CT images generated from UTE MRI by a generative adversarial network (GAN). Materials and Methods This retrospective study included patients with cystic fibrosis (CF) who underwent both UTE MRI and CT on the same day at one of six institutions between January 2018 and December 2022. The two-dimensional GAN algorithm was trained using paired MRI and CT sections and tested, along with an external data set. Image quality was assessed quantitatively by measuring apparent contrast-to-noise ratio, apparent signal-to-noise ratio, and overall noise and qualitatively by using visual scores for features including artifacts. Two readers evaluated CF-related structural abnormalities and used them to determine clinical Bhalla scores. Results The training, test, and external data sets comprised 82 patients with CF (mean age, 21 years ± 11 [SD]; 42 male), 28 patients (mean age, 18 years ± 11; 16 male), and 46 patients (mean age, 20 years ± 11; 24 male), respectively. In the test data set, the contrast-to-noise ratio of synthetic CT images (median, 303 [IQR, 221-382]) was higher than that of UTE MRI scans (median, 9.3 [IQR, 6.6-35];
Indexed as
Cystic FibrosisAdolescentAdultChildFemaleHumansLungMagnetic Resonance ImagingMaleRetrospective StudiesTomography, X-Ray ComputedYoung Adult
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