Evidence map›Paper›PMID 37403612›Full record

ArticleJournal of surgical oncology2023

Association between travel distance and overall survival among patients with adrenocortical carcinoma.

Charles D Logan, Sara E A Nunnally, Catherine Valukas, Samantha Warwar, Joanna T Swinarska, Frances T Lee, David J Bentrem, David D Odell, Dina M Elaraj, Cord Sturgeon

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Charles D LoganDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Sara E A NunnallyDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Catherine ValukasDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Samantha WarwarDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Joanna T SwinarskaDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Frances T LeeDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
David J BentremDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
David D OdellDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Dina M ElarajDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.
Cord SturgeonDepartment of Surgery, Northwestern Quality Improvement, Research, & Education in Surgery (NQUIRES), Northwestern Medicine, Chicago, Illinois, USA.

Funding

Northwestern University Minority Health and Health Disparities Research Training (NU-MHRT)T37MD014248 · NIMHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SIMON, MELISSA A. · 2019 to 2023
$1.4M
COllaborative Northwestern Surgical Oncology Research Training (CONSORT)T32CA247801 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ACKERMANN, RONALD T., KHAN, SEEMA AHSAN · 2020 to 2024
$1.3M
Surgical Multispecialty Access to Research in Residency Training (SMART)R38CA245095 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KHAN, SEEMA AHSAN · 2021 to 2024
$1.0M
Development of a Novel Statewide Learning Collaborative to Increase Lung Cancer Guideline Adherence and Improve Cancer Care DeliveryK07CA216330 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ODELL, DAVID D. · 2017 to 2021
$836k
NCI NIH HHS K07 CA216330NCI NIH HHS R38 CA245095NCI NIH HHS T32 CA247801NIMHD NIH HHS T37 MD014248
6 · The paper itself

Abstract

BACKGROUND AND

objectivesRegionalization of care is associated with improved perioperative outcomes after adrenalectomy. However, the relationship between travel distance and treatment of adrenocortical carcinoma (ACC) is unknown. We investigated the association between travel distance, treatment, and overall survival (OS) among patients with ACC.

methodsPatients diagnosed with ACC between 2004 and 2017 were identified with the National Cancer Database. Long distance was defined as the highest quintile of travel (≥42.2 miles). The likelihood of surgical management and adjuvant chemotherapy (AC) were determined. The association between travel distance, treatment, and OS was evaluated.

resultsOf 3492 patients with ACC included, 2337 (66.9%) received surgery. Rural residents were more likely to travel long distances for surgery than metropolitan residents (65.8% vs. 15.5%, p < 0.001), and surgery was associated with improved OS (HR 0.43, 95% CI 0.34-0.54). Overall, 807 (23.1%) patients received AC with rates decreasing approximately 1% per 4-mile travel distance increase. Also, long distance travel was associated with worse OS among surgically treated patients (HR 1.21, 95% CI 1.05-1.40).

conclusionsSurgery was associated with improved overall survival for patients with ACC. However, increased travel distance was associated with lower likelihood to receive adjuvant chemotherapy and decreased overall survival.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaChemotherapy, AdjuvantHumansadrenalectomyrural populationtravel

Identifiers

PMID37403612
PMCPMC10997292

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.