Evidence map›Paper›PMID 37403327›Full record

ArticleJournal of clinical and experimental neuropsychology2023

Assessing subjective cognitive decline in older adults attending primary health care centers: what question should be asked?

Matías Molina-Donoso, Teresa Parrao, Céline Meillon, Daniela Thumala, Patricia Lillo, Roque Villagra, Agustín Ibañez, Mauricio Cerda, Pedro Zitko, Hélène Amieva and 1 more

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matías Molina-DonosoGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.
Teresa ParraoGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.
Céline MeillonINSERM, Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Bordeaux, France.
Daniela ThumalaGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.
Patricia LilloGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.
Roque VillagraGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.
Agustín IbañezLatin American Brain Health Institute (BrainLat), University Adolfo Ibáñez, Santiago, Chile.
Mauricio CerdaBiomedical Neuroscience Institute, Santiago, Chile.
Pedro ZitkoGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.
Hélène AmievaINSERM, Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Bordeaux, France.
Andrea SlachevskyGerosciences Center for Brain Health and Metabolism (GERO), Santiago, Chile.

Funding

US-South American Initiative for Genetic-Neural-Behavioral Interactions in Human Neurodegenerative ResearchR01AG057234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Claudia Duran-Aniotz, Agustin M. Ibanez · 2019 to 2026
$6.1M
NIA NIH HHS R01 AG057234
6 · The paper itself

Abstract

introductionSubjective Cognitive Decline (SCD) refers to a self-perceived experience of decreased cognitive function without objective signs of cognitive impairment in neuropsychological tests or daily living activities. Despite the abundance of instruments addressing SCD, there is no consensus on the methods to be used. Our study is founded on 11 questions selected due to their recurrence in most instruments. The objective was to determine which one of these questions could be used as a simple screening tool.

methods189 participants aged 65 and over selected from Primary Care centers in Santiago de Chile responded to these 11 questions and were evaluated with the MiniMental State Examination (MMSE), the Free and Cued Selective Reminding Test (FCSRT), the Pfeffer functional scale, and the Geriatric Depression Scale (GDS). An Item ResponseTheory (IRT) method was performed to assess the contribution of each of the 11 questions to the SCD latent trait and its discrimination ability.

resultsBased on the results of the exploratory factor analysis showing very high/low saturation of several questions on the factors, and the high residual correlation between some questions, the IRT methods led to select one question ("Do you feel like your memory has become worse?") which revealed to be the most contributive and discriminant. Participants who answered yes had a higher GDS score. There was no association with MMSE, FCSRT, and Pfeffer scores.

conclusionThe question "Do you feel like your memory has become worse?" may be a good proxy of SCD and could be included in routine medical checkups.

Indexed as

Cognitive DysfunctionAgedCognitionCuesHumansNeuropsychological TestsPrimary Health Careitem response theory (IRT)mild cognitive impairmentneurocognitive disordersolder adultsSubjective cognitive decline

Identifiers

PMID37403327
PMCPMC11195299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.