Evidence map›Paper›PMID 37403243›Full record

ReviewRevista de neurologia2023

[15th Post-ECTRIMS Meeting: a review of the latest developments presented at the 2022 ECTRIMS Congress (Part II)].

O Fernández, X Montalban, E Agüera, Y Aladro, A Alonso, R Arroyo, L Brieva, C Calles, L Costa-Frossard, S Eichau and 14 more

Open access · greenAbstract readEnglish AbstractReview
In one paragraph

Review in Revista de neurologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 1 country.

O FernándezHospital Regional Universitario de Málaga, Málaga, España.
X MontalbanHospital Universitari Vall d'Hebron-CEMCAT, Barcelona, España.
E AgüeraHospital Universitario Reina Sofía, Madrid, España.
Y AladroHospital Universitario de Getafe, 28905 Getafe, España.
A AlonsoHospital Regional Universitario de Málaga, Málaga, España.
R ArroyoHospital Universitario Quirónsalud, Madrid, España.
L BrievaHospital Universitari Arnau de Vilanova-Universitat de Lleida, Lleida, España.
C CallesHospital Universitari Son Espases, Palma de Mallorca, España.
L Costa-FrossardHospital Universitario Ramón y Cajal, Madrid, España.
S EichauHospital Universitario Virgen Macarena, 41003 Sevilla, España.
J M García-DomínguezHospital Universitario Gregorio Marañón, Madrid, España.
M A HernándezHospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
L LandeteHospital Universitario Doctor Peset, Valencia, España.
M LlanezaComplejo Hospitalario Universitario de Ferrol, Ferrol, España.
S LlufriuHospital Clínic de Barcelona-IDIBAPS, Barcelona, España.
J E Meca-LallanaHospital Clínico Universitario Virgen de la Arrixaca, Murcia, España.
V Meca-LallanaHospital Universitario de La Princesa, 28006 Madrid, España.
N Mongay-OchoaHospital Universitari Vall d'Hebron-CEMCAT, Barcelona, España.
E MoralHospital Sant Joan Despí Moisés Broggi, Sant Joan Despí, España.
C Oreja-GuevaraHospital Clínico San Carlos-IDISSC-UCM, Madrid, España.
Ll Ramió-TorrentàUniversitat de Girona, Girona, España.
N TéllezHospital Clínico Universitario de Valladolid, Valladolid, España.
L Romero-PinelHospital Universitari de Bellvitge-IDIBELL, L´Hospitalet de Ll., España.
A Rodríguez-AntigüedadHospital Universitario Cruces, Bilbao, España.
Hospital Regional Universitario de Málaga · ESHospital Universitario Nuestra Señora de Candelaria · ESHospital Clínico Universitario de Valladolid · ESHospital de Cruces · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario Doctor Peset · ESHospital Universitario Quirónsalud Madrid · ESHospital Universitario Ramón y Cajal · ESHospital Universitario Reina Sofía · ESHospital Universitario Virgen de la Arrixaca · ESUniversitat de Girona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOn 4 and 5 November 2022, Madrid hosted the 15th edition of the Post-ECTRIMS Meeting, where neurologists specialised in multiple sclerosis outlined the latest developments presented at the 2022 ECTRIMS Congress, held in Amsterdam from 26 to 28 October.

aimTo synthesise the content presented at the 15th edition of the Post-ECTRIMS Meeting, in an article broken down into two parts. DEVELOPMENT: This second part describes the new developments in terms of therapeutic strategies for escalation and de-escalation of disease-modifying therapies (DMT), when and in whom to initiate or switch to highly effective DMT, the definition of therapeutic failure, the possibility of treating radiologically isolated syndrome and the future of personalised treatment and precision medicine. It also considers the efficacy and safety of autologous haematopoietic stem cell transplantation, different approaches in clinical trial design and outcome measures to assess DMT in progressive stages, challenges in the diagnosis and treatment of cognitive impairment, and treatment in special situations (pregnancy, comorbidity and the elderly). In addition, results from some of the latest studies with oral cladribine and evobrutinib presented at ECTRIMS 2022 are shown.

Indexed as

Cognitive DysfunctionHematopoietic Stem Cell TransplantationMultiple SclerosisAgedFemaleForecastingHumansPregnancy

Identifiers

PMID37403243
PMCPMC10662183
OpenAlexW4383186140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.