Evidence map›Paper›PMID 37403223›Full record

ArticleExperimental neurobiology2023

Monitoring α-synuclein Aggregation Induced by Preformed α-synuclein Fibrils in an

Beom Jin Kim, Hye Rin Noh, Hyongjun Jeon, Sang Myun Park

Open access · diamondAbstract read
In one paragraph

Article in Experimental neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Beom Jin KimDepartment of Pharmacology, Ajou University School of Medicine, Suwon 16499, Korea.
Hye Rin NohDepartment of Pharmacology, Ajou University School of Medicine, Suwon 16499, Korea.
Hyongjun JeonCenter for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon 16499, Korea.
Sang Myun ParkDepartment of Pharmacology, Ajou University School of Medicine, Suwon 16499, Korea.
Ajou University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is characterized by the presence of α-synuclein (α-syn) inclusions in the brain and the degeneration of dopamine-producing neurons. There is evidence to suggest that the progression of PD may be due to the prion-like spread of α-syn aggregates, so understanding and limiting α-syn propagation is a key area of research for developing PD treatments. Several cellular and animal model systems have been established to monitor α-syn aggregation and propagation. In this study, we developed an

Indexed as

In vitro techniquesParkinson diseaseProtein aggregationα-synuclein

Identifiers

PMID37403223
PMCPMC10327928
OpenAlexW4383187667

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.