ArticleDiagnostic pathology2023
Reticular fibre structure in the differential diagnosis of parathyroid neoplasms.
Article in Diagnostic pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Shear wave elastography can improve the preoperative diagnosis of parathyroid carcinoma or atypical parathyroid tumor: initial experience.BMC medical imaging · 2026Article
- Avoiding overdiagnosis of parathyroid carcinoma.Virchows Archiv : an international journal of pathology · 2026Review
- Reticulin Framework Assessment in Neoplastic Endocrine Pathology.Endocrine pathology · 2025Review
- Analysis of Histochemical Characteristics of Submandibular Gland of the Bactrian Camel.Veterinary sciences · 2025Article
- A novel mutation in PTEN in anaplastic thyroid carcinoma: A case report.Biomedical reports · 2024Article
- Bone marrow fibrosis in newly diagnosed multiple myeloma and its correlation with clinicopathological factors.Diagnostic pathology · 2024Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundTo investigate the characteristics of reticular fibre structure (RFS) in parathyroid adenoma (PTA), atypical parathyroid tumour (APT), and parathyroid carcinoma (PTC), and to assess its value as a diagnostic indicator.
methodsClinical data and pathological specimens of patients with PTA, APT or PTC were collected. Reticular fibre staining was performed to observe the characteristics of RFS. This study evaluated the incidence of RFS destruction in parathyroid tumours, compared RFS destruction between primary PTC and recurrent and metastatic PTC, and explored the association between RFS destruction and clinicopathological features of APT and primary PTC.
resultsReticular fibre staining was performed in 50 patients with PTA, 25 patients with APT, and 36 patients with PTC. In PTA cases, a delicate RFS was observed. In both the APT and PTC groups, incomplete RFS areas were observed. The incidence of RFS destruction was different among the PTA, APT, and PTC groups (P < 0.001, χ
conclusionRFS destruction may indicate that parathyroid tumours have unfavourable biological behaviours.Reticular fibre staining may be a valuable tool for improving the diagnostic accuracy in parathyroid tumours.
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