Evidence map›Paper›PMID 37403100›Full record

ArticleBMC medical research methodology2023

Effect of alcohol consumption on breast cancer: probabilistic bias analysis for adjustment of exposure misclassification bias and confounders.

Reza Pakzad, Saharnaz Nedjat, Hamid Salehiniya, Nasrin Mansournia, Mahyar Etminan, Maryam Nazemipour, Iraj Pakzad, Mohammad Ali Mansournia

Abstract read
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Article in BMC medical research methodology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reza PakzadDepartment of Epidemiology, Faculty of Health, Ilam University of Medical Sciences, Ilam, Iran.
Saharnaz NedjatDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, PO Box: 14155-6446, Tehran, Iran.
Hamid SalehiniyaDepartment of Epidemiology and Biostatistics, School of Health, Birjand University of Medical Sciences, South Khorasan, Iran.
Nasrin MansourniaDepartment of Endocrinology, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Mahyar EtminanDepartments of Ophthalmology and Visual Sciences, Medicine and Pharmacology, University of British Columbia, Vancouver, Canada.
Maryam NazemipourDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, PO Box: 14155-6446, Tehran, Iran.
Iraj PakzadDepartment of Microbiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Mohammad Ali MansourniaDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, PO Box: 14155-6446, Tehran, Iran. mansournia_ma@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was conducted to evaluate the effect of alcohol consumption on breast cancer, adjusting for alcohol consumption misclassification bias and confounders.

methodsThis was a case-control study of 932 women with breast cancer and 1000 healthy control. Using probabilistic bias analysis method, the association between alcohol consumption and breast cancer was adjusted for the misclassification bias of alcohol consumption as well as a minimally sufficient set of adjustment of confounders derived from a causal directed acyclic graph. Population attributable fraction was estimated using the Miettinen's Formula.

resultsBased on the conventional logistic regression model, the odds ratio estimate between alcohol consumption and breast cancer was 1.05 (95% CI: 0.57, 1.91). However, the adjusted estimates of odds ratio based on the probabilistic bias analysis ranged from 1.82 to 2.29 for non-differential and from 1.93 to 5.67 for differential misclassification. Population attributable fraction ranged from 1.51 to 2.57% using non-differential bias analysis and 1.54-3.56% based on differential bias analysis.

conclusionA marked measurement error was in self-reported alcohol consumption so after correcting misclassification bias, no evidence against independence between alcohol consumption and breast cancer changed to a substantial positive association.

Indexed as

Breast NeoplasmsAlcohol DrinkingBiasCase-Control StudiesCausalityFemaleHumansAlcohol consumptionBreast cancerMonte-Carlo sensitivity analysisPopulation attributable fractionProbabilistic bias analysis

Identifiers

PMID37403100
PMCPMC10318777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.