Evidence map›Paper›PMID 37403088›Full record

ArticleVeterinary research2023

Evaluation of the performance of the IFN-γ release assay in bovine tuberculosis free herds from five European countries.

Alberto Gomez-Buendia, Beatriz Romero, Javier Bezos, José Luis Saez, Ivonne Archetti, Maria Lodovica Pacciarini, Maria Laura Boschiroli, Sébastien Girard, Emanuela Gutu, Florica Barbuceanu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Exploring specific biomarkers in blood forFrontiers in microbiology · 2026
    Article
  6. Article
  7. Bovine tuberculosis reactor cattle in Southwest Ethiopia: Risk factors for bovine tuberculosis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

Alberto Gomez-BuendiaVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain.
Beatriz RomeroVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain. bromerom@visavet.ucm.es.ORCID http://orcid.org/0000-0001-5263-1806
Javier BezosVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain.
José Luis SaezSubdirección General de Sanidad e Higiene Animal y Trazabilidad, Dirección General de la Producción Agraria, Ministerio de Agricultura, Pesca y Alimentación, Madrid, Spain.
Ivonne ArchettiNational Reference Centre for Bovine Tuberculosis, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Brescia, Italy.
Maria Lodovica PacciariniNational Reference Centre for Bovine Tuberculosis, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Brescia, Italy.
Maria Laura BoschiroliUniversity Paris-Est, Laboratory for Animal Health, Tuberculosis National Reference Laboratory, ANSES, Maisons-Alfort, France.
Sébastien GirardRegional Directorate for Food, Agriculture and Forest of Bourgogne-Franche-Comte, Dijon, France.
Emanuela GutuInstitute for Diagnosis and Animal Health, Bucharest, Romania.
Florica BarbuceanuInstitute for Diagnosis and Animal Health, Bucharest, Romania.
Ourania KaraoulaniNational Reference Laboratory for Bovine Tuberculosis, Directorate of Veterinary Centre of Athens, Ministry of Rural Development and Food, Athens, Greece.
Athanasia StournaraDepartment of Serology, Veterinary Laboratory of Larissa, Ministry of Rural Development and Food, Larissa, Greece.
Lucia de JuanVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain.
Julio AlvarezVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain.
Universidad Complutense de Madrid · ESHellenic Ministry of Rural Development and Food · GRInstitute for Diagnosis and Animal Health · ROIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" · ITDépartement Santé Animale · FRMinisterio de Agricultura, Pesca y Alimentación · ES

Funding

Ministerio de Ciencia, Innovación y Universidades RTI2018-096010-B-C22Ministerio de Economía, Industria y Competitividad RYC-2016-20422Universidad Complutense de Madrid CT58/21-CT59/21
6 · The paper itself

Abstract

The diagnostic methods for granting and maintenance of the official tuberculosis-free (OTF) status and for intra-Community movement of cattle are the tuberculin skin tests (single or comparative) and the interferon-γ (IFN-γ) release assay (IGRA). However, until now, IGRAs have been primarily applied in infected farms in parallel to the skin test to maximize the number of infected animals detected. Therefore, an evaluation of the performance of IGRAs in OTF herds to assess whether if their specificity is equal to or higher than that of the skin tests is needed. For this, a panel of 4365 plasma samples coming from 84 OTF herds in six European regions (five countries) was assembled and analysed using two IGRA kits, the ID Screen

Indexed as

Cattle DiseasesMycobacterium bovisTuberculosis, BovineAnimalsBayes TheoremCattleInterferon-gammaInterferon-gamma Release TestsSensitivity and SpecificityTuberculin TestInterferon-gammaBayesian statisticsBovine tuberculosiscut-offinterferon-gamma release assayMycobacterium tuberculosis complexspecificity

Identifiers

PMID37403088
PMCPMC10320920
OpenAlexW4383104961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.