Evidence map›Paper›PMID 37402946›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2023

Lower-limb intramedullary nailing in patients with polyostotic fibrous dysplasia who had a previous unsuccessful treatment. A report of 48 cases.

E Ippolito, P Farsetti, R Caterini, G Gorgolini, A Caterini, F De Maio

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In one paragraph

Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

E IppolitoDepartment of Clinical Science and Traslational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy. profernestoippolito@gmail.com.ORCID http://orcid.org/0000-0002-3706-7693
P FarsettiDepartment of Clinical Science and Traslational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.
R CateriniDepartment of Clinical Science and Traslational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.
G GorgoliniDepartment of Clinical Science and Traslational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.
A CateriniDepartment of Clinical Science and Traslational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.
F De MaioDepartment of Clinical Science and Traslational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary nailing (IN) seems to be the best primary surgical treatment for patients with either polyostotic fibrous dysplasia or McCune-Albright syndrome (PFD/MAS) when the femur and tibia are totally affected by fibrous dysplasia (FD) and pain, fracture and deformity are likely to occur. However, other management protocols have been applied in these cases, often leading to disabling sequelae. This study sought to evaluate if IN could also have been effective as a salvage procedure to provide patients with satisfactory results, regardless of the poor results due to the improper treatment previously performed. MATERIALS AND

methodsTwenty-four retrospectively registered PFD/MAS patients with 34 femurs and 14 tibias totally affected by fibrous dysplasia had received various treatments with unsatisfactory results in other institutions. Before the IN performed in our hospital, 3 patients were wheelchair bound; 4 were fractured; 17 limped; and many used an aid for walking. Salvage IN was performed in our hospital at a mean patient age of 23.66 ± 6.06 years (range, 15-37 years). The patients were evaluated before-except for the four fractured ones-and after IN using the validated Jung scoring system, and the data were statistically analyzed.

resultsThe mean length of follow-up after IN was 9.12 ± 3.68 years (range, 4-17 years). The patients' mean Jung score significantly improved from 2.52 ± 1.74 points before IN to 6.78 ± 2.23 at follow-up (p < 0.05). Ambulation was improved in ambulatory patients and restored in wheelchair users. The complication rate was 21%.

conclusionsRegardless of the high rate of complications, IN may be considered a reliable surgical procedure to salvage a failed treatment in PFD/MAS, with long-lasting satisfactory results achieved in most patients. Trial registration statement: Not applicable. LEVEL OF EVIDENCE: IV.

Indexed as

Fibrous Dysplasia, PolyostoticFracture Fixation, IntramedullaryFractures, BoneAdolescentAdultFemurHumansLower ExtremityYoung AdultLower limb deformityLower limb fractureMcCune–Albright syndromePolyostotic fibrous dysplasiaSalvage intramedullary nailing

Identifiers

PMID37402946
PMCPMC10319686
OpenAlexW4383070376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.