Evidence map›Paper›PMID 37402224›Full record

ArticleScience signaling2023

Centralspindlin-mediated transport of RhoGEF positions the cleavage plane for cytokinesis.

Brandt Warecki, Li Tao

Open access · greenAbstract read
In one paragraph

Article in Science signaling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Brandt WareckiDepartment of Biology, University of Hawai'i at Hilo, Hilo, HI 96720, USA.ORCID 0000-0002-8025-6246
Li TaoDepartment of Biology, University of Hawai'i at Hilo, Hilo, HI 96720, USA.ORCID 0009-0004-8275-2210
University of California, Santa Cruz · USUniversity of Hawaii at Hilo · US

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI HELEN C TURNER · 2012 to 2026
$60.3M
UCSC PREPR25GM104552 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI William T. SULLIVAN · 2013 to 2026
$3.9M
Mitotic transmission of acentric chromosomesR35GM139595 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI William T. SULLIVAN · 2021 to 2026
$2.5M
NIGMS NIH HHS P20 GM103466NIGMS NIH HHS R25 GM104552NIGMS NIH HHS R35 GM139595
6 · The paper itself

Abstract

During cytokinesis, the cell membrane furrows inward along a cleavage plane. The positioning of the cleavage plane is critical to faithful cell division and is determined by the Rho guanine nucleotide exchange factor (RhoGEF)-mediated activation of the small guanosine triphosphatase RhoA and the conserved motor protein complex centralspindlin. Here, we explored whether and how centralspindlin mediates the positioning of RhoGEF. In dividing neuroblasts from

Indexed as

CytokinesisDrosophila ProteinsAnimalsDrosophila melanogasterMicrotubulesRho Guanine Nucleotide Exchange FactorsSpindle ApparatusDrosophila ProteinsRho Guanine Nucleotide Exchange Factors

Identifiers

PMID37402224
PMCPMC10501416
OpenAlexW4383070555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.