ArticleInfection2024
Risk of embolic events before and after antibiotic treatment initiation among patients with left-side infective endocarditis.
Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Percutaneous Vacuum-Assisted Debulking of Infected and Non-Infected Left-Sided Cardiac Masses Using the AngioVac System: A Systematic Review of Published Case Reports and Case Series.Journal of clinical medicine · 2026Review
- Embolic Burden and Echocardiographic Predictors in a Real-World Cohort of Infective Endocarditis: A 15-Year Single-Center Retrospective Study.Journal of clinical medicine · 2026Article
- Mind the Gap: Inadequate Performance of Embolic Risk Scores in Infective Endocarditis.Open forum infectious diseases · 2026Article
- Infective Endocarditis and Antimicrobial Timing: A Case for Delay?Open forum infectious diseases · 2025Article
- Optimal surgical timing for non-urgent surgery patients with active infective endocarditis.Nagoya journal of medical science · 2025Article
- Deciphering the Complex Relationships Between the Hemostasis System and Infective Endocarditis.Journal of clinical medicine · 2025Review
- Predictors of Visceral Infectious Aneurysms in Patients with Infective Endocarditis and Systemic Embolization.Journal of cardiovascular development and disease · 2025Article
- Embolic risk management in infective endocarditis: predicting the 'embolic roulette'.Open heart · 2025Review
- Pathogenic spectrum of infective endocarditis and analysis of prognostic risk factors following surgical treatment in a tertiary hospital in China.BMC infectious diseases · 2024Article
- Review
- Eyes Wide Shut: A Cohort Study Questioning the Role of Fundoscopy in Infective Endocarditis Diagnosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Cryoglobulinemic vasculitis triggered byFrontiers in immunology · 2024Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEmbolic events (EEs) are a common complication of left-side infective endocarditis (IE). The aim of the present study was to identify risk factors for the occurrence of EEs before or after antibiotic treatment instauration among patients with definite or possible IE.
methodsThis retro-prospective study was conducted at the Lausanne University Hospital, Lausanne, Switzerland, from January 2014 to June 2022. EEs and IE were defined according to modified Duke criteria.
resultsA total of 441 left-side IE episodes were included (334: 76% were definite and 107; 24% possible IE). EE were diagnosed in 260 (59%) episodes; in 190 (43%) before antibiotic treatment initiation and 148 (34%) after. Central nervous system (184; 42%) was the most common site of EE. Multivariable analysis identified S. aureus (P 0.022), immunological phenomena (P < 0.001), sepsis (P 0.027), vegetation size ≥ 10 mm (P 0.003) and intracardiac abscess (P 0.022) as predictors of EEs before antibiotic treatment initiation. For EEs after antibiotic treatment initiation, multivariable analysis revealed vegetation size ≥ 10 mm (P < 0.001), intracardiac abscess (P 0.035) and prior EE (P 0.042), as independent predictors of EEs, while valve surgery (P < 0.001) was associated with lower risk for EEs.
conclusionsWe reported a high percentage of EEs among patients with left-side IE; vegetation size, intracardiac abscess, S. aureus and sepsis were independently associated with the occurrence of EEs. In addition to antibiotic treatment, early surgery led to further decrease in EEs incidence.
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