Evidence map›Paper›PMID 37401998›Full record

ReviewApplied microbiology and biotechnology2023

Phoma spp. an untapped treasure of cytotoxic compounds: current status and perspectives.

Mahendra Rai, Beata Zimowska, Aniket Gade, Pramod Ingle

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Draft genome sequence of the endophytic fungusMicrobiology resource announcements · 2024
    Article
  3. Exploration of Endophytic Fungal Communities in ThreeIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahendra RaiBiotechnology Department, Sant Gadge Baba Amravati University, Amravati, 444 602, Maharashtra, India. mahendrarai@sgbau.ac.in.ORCID http://orcid.org/0000-0003-0291-0422
Beata ZimowskaDepartment of Plant Protection, University of Life Sciences in Lublin, Poland7 K. St. Leszczyńskiego Street, 20-069, Lublin, Poland.ORCID http://orcid.org/0000-0001-5524-7623
Aniket GadeBiotechnology Department, Sant Gadge Baba Amravati University, Amravati, 444 602, Maharashtra, India.ORCID http://orcid.org/0000-0002-1966-999X
Pramod IngleBiotechnology Department, Sant Gadge Baba Amravati University, Amravati, 444 602, Maharashtra, India.ORCID http://orcid.org/0000-0003-2801-6939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genus Phoma has been explored for a wide range of secondary metabolites signifying a huge range of bioactivities. Phoma sensu lato is a major group that secretes several secondary metabolites. The genus Phoma mainly includes Phoma macrostoma, P. multirostrata, P. exigua, P. herbarum, P. betae, P. bellidis, P. medicaginis, P. tropica, and many more species from the genus that are continuously being identified for their potential secondary metabolites. The metabolite spectrum includes bioactive compounds like phomenon, phomin, phomodione, cytochalasins, cercosporamide, phomazines, and phomapyrone reported from various Phoma spp. These secondary metabolites show a broad range of activities including antimicrobial, antiviral, antinematode, and anticancer. The present review is aimed to emphasize the importance of Phoma sensu lato fungi, as a natural source of biologically active secondary metabolites, and their cytotoxic activities. So far, cytotoxic activities of Phoma spp. have not been reviewed; hence, this review will be novel and useful for the readers to develop Phoma-derived anticancer agents. KEY POINTS: • Different Phoma spp. contain a wide variety of bioactive metabolites. • These Phoma spp. also secrete cytotoxic and antitumor compounds. • The secondary metabolites can be used for the development of anticancer agents.

Indexed as

Antineoplastic AgentsPhomaAntineoplastic AgentsAnticancerCytotoxicityPhoma spp.Secondary metabolites

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.