Evidence map›Paper›PMID 37401789›Full record

ArticleJournal of the American Geriatrics Society2023

Associations of sex, Alzheimer's disease and related dementias, and days alive and at home among older Medicare beneficiaries recovering from hip fracture.

Heather L Mutchie, Denise L Orwig, Ann L Gruber-Baldini, Abree Johnson, Jay Magaziner, Jason R Falvey

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Impact of traumatic brain injury on recovery over the year following hip fracture among older Medicare beneficiaries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heather L MutchieDepartment of Epidemiology & Public Health, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-6964-5283
Denise L OrwigDepartment of Epidemiology & Public Health, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Ann L Gruber-BaldiniDepartment of Epidemiology & Public Health, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Abree JohnsonDepartment of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Jay MagazinerDepartment of Epidemiology & Public Health, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Jason R FalveyDepartment of Epidemiology & Public Health, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-9063-0617
University of Maryland, Baltimore · US

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
Community Ambulation Following Hip FractureR01AG035009 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 2010 to 2016
$11.0M
RESEARCH TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000262 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ANN L GRUBER-BALDINI, DENISE L ORWIG · 1998 to 2026
$8.2M
The Epidemiology of Bone Strength and Muscle Composition After Hip Fracture in MeR01AG029315 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 2007 to 2011
$4.1M
The ENRICH Study: Engaging Community and Municipal Services to Promote High Quality Aging in Place After Hip FractureK76AG074926 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI FALVEY, JASON RAYMOND · 2021 to 2025
$1.4M
ACL HHS 90EJIG0010-01-01NCATS NIH HHS UL1 TR003098NIA NIH HHS K76 AG074926NIA NIH HHS L30 AG057095NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG029315NIA NIH HHS R01 AG035009NIA NIH HHS R37 AG009901NIA NIH HHS T32 AG000262
6 · The paper itself

Abstract

backgroundMales constitute 25% of older adults who experience hip fractures in the United States; a concerning upward trend given poorer health and outcomes among male survivors. Male sex is associated with worse cognitive performance after hip fracture, impacting participation in rehabilitation and long-term outcomes especially for those with Alzheimer's disease or related dementias (ADRD). However, little research has evaluated whether sex differences in post-fracture recovery are greater among those living with ADRD.

methodsData were drawn from 2010 to 2017 Medicare fee-for-service beneficiaries aged 65 years and older who survived hospitalization for hip fracture (n = 69,581). The primary outcome was days alive and at home (DAAH), a validated patient-centered claims-based outcome calculated as 365 days from fracture minus days in hospital, nursing home, rehabilitation facility, emergency department, or time after death. Multivariable Poisson regressions with an interaction term between sex and ADRD status were to model the association between DAAH and ADRD in the 12 months post hip fracture, adjusting for demographics, injury severity, chronic disease burden, and hospital-level fixed effects.

resultsCompared to females, males were younger and had more comorbidities at the time of fracture. Among survivors, males with ADRD spent a mean of 160.7 DAAH compared to 228.4 for males without ADRD, 177.8 for females with ADRD, and 248.0 for females without ADRD. In adjusted analyses, males without ADRD spent 8.2% fewer DAAH compared to females (rate ratio [RR] = 0.92, 95% CI 0.92-0.92). This relative sex difference increased significantly when comparing those living with ADRD, with males spending an additional 3.3% fewer DAAH (interaction RR = 0.96, 95% CI 0.96-0.97).

conclusionsMales spend fewer DAAH after hip fracture than females, and this difference increases modestly for males living with ADRD compared to females. This suggests that cognitive impairment may be a small but significant contributor to sex-based differences observed during hip fracture recovery.

Indexed as

Alzheimer DiseaseHip FracturesAgedFemaleHospitalizationHumansMaleMedicareNursing HomesUnited Statescognitive impairmenthip fracturepatient-centered outcomessexsex differences

Identifiers

PMID37401789
PMCPMC11087867
OpenAlexW4383059209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.