Evidence map›Paper›PMID 37401788›Full record

ArticleJournal of diabetes science and technology2025

Selective Collection of Exhaled Breath Condensate for Noninvasive Screening of Breath Glucose.

Aditya Desai, Divya Tankasala, Gabriel P Ng, Pankti Thakkar, Orlando S Hoilett, Kieren J Mather, Jacqueline C Linnes

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes science and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Applications and prospects of biomaterials in diabetes management.Frontiers in bioengineering and biotechnology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aditya DesaiPurdue University, West Lafayette, IN, USA.ORCID 0000-0002-7065-1488
Divya TankasalaPurdue University, West Lafayette, IN, USA.
Gabriel P NgPurdue University, West Lafayette, IN, USA.
Pankti ThakkarPurdue University, West Lafayette, IN, USA.
Orlando S HoilettPurdue University, West Lafayette, IN, USA.
Kieren J MatherIndiana University School of Medicine, Indianapolis, IN, USA.
Jacqueline C LinnesPurdue University, West Lafayette, IN, USA.
Purdue University West Lafayette · USIndiana University School of Medicine

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Non-invasive optical detection of cerebral hemodynamics and metabolic transientsR21EB020347 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI FANTINI, SERGIO · 2016 to 2017
$401k
NIBIB NIH HHS R21 EB020347NIDDK NIH HHS P30 DK097512
6 · The paper itself

Abstract

backgroundAlthough exhaled breath condensate (EBC) is a promising noninvasive sample for detecting respiratory analytes such as glucose, current EBC collection methods yield inconsistent results.

methodsWe developed a custom EBC collection device with a temperature-based algorithm to selectively condense alveolar air for reproducible EBC glucose detection. We characterized the condensate volumes and the corresponding glucose concentrations. We performed a pilot study demonstrating its use during oral glucose tolerance tests.

resultsThe novel device selectively captured alveolar air resulting in slightly higher and less variable glucose concentrations than the overall EBC. Participants with type 2 diabetes demonstrated significantly higher blood plasma-EBC glucose ratios than normoglycemic participants.

conclusionsTemperature-based selective EBC collection allows EBC glucose measurement and is a promising sampling method to distinguish patients with and without diabetes.

Indexed as

Breath TestsDiabetes Mellitus, Type 2ExhalationAdultBlood GlucoseFemaleGlucoseGlucose Tolerance TestHumansMaleMiddle AgedPilot ProjectsSpecimen HandlingBlood GlucoseGlucoseexhaled breath condensateglucosepoint-of-care diagnosticstype 2 diabetes

Identifiers

PMID37401788
PMCPMC11688680
OpenAlexW4383058514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.