ArticleActa veterinaria Scandinavica2023
Gastro-intestinal lesions are not relatable to diarrhoea or specific pathogens in post-weaning diarrhoea (PWD) in pigs.
Article in Acta veterinaria Scandinavica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 17 citations in OpenAlex.
- Comparative evaluation of post-mortem methods for detection of diarrhoea in early-life piglets.Porcine health management · 2026Article
- Metagenomics provides broad detection of pathogens, antimicrobial resistance, and virulence genes in pig diarrhoea and complement conventional methods.Animal microbiome · 2026Article
- Faecal microbiome profiling uncovers putative biomarkers for piglets resilient to post-weaning diarrhoea.Animal microbiome · 2026Article
- Machine-learning for quantitative histopathology of piglet intestinal tissues: challenges with limited training data.Frontiers in veterinary science · 2025Article
- RGB-based machine vision for enhanced pig disease symptoms monitoring and health management: a review.Journal of animal science and technology · 2025Review
- An observational field study of porcine post-weaning diarrhea: clinical and microbiological findings, and fecal pH-measurements as a potential diagnostic tool.Porcine health management · 2023Article
- Lesions and pathogens found in pigs that died during the nursery period in five Danish farms.Porcine health management · 2023Article
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13 authors at 1 institution in 1 country.
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Abstract
backgroundPost-weaning diarrhoea (PWD) is a multifactorial condition and the most well documented infectious cause is enterotoxigenic Escherichia coli. The objective of the study was to investigate possible associations between pathological manifestations and pathogens in pigs with and without PWD. The study was conducted as a case-control study and included a total of 173 pigs from 9 different commercial intensive indoor production herds in eastern Denmark.
resultsBased on clinical examination, a total of 89 piglets with PWD (cases) and 84 piglets without PWD (controls) were included. Most of the pigs (n = 105/173) presented gastric lesions, which were more frequently observed in the control group. The odds of gastric ulcers were lower among pigs with PWD compared to pigs without PWD with an odds ratio (OR) of 0.2 (0.0; 0.7). Abnormal content in the colon was associated with PWD, with an OR of 6.5 (3.2; 14.3). No apparent association was found between lesions and the various pathogens or a combination of these. The odds of neutrophilic granulocyte infiltration were lower in the jejunum among pigs with PWD (OR 0.3 [0.1; 0.6]) compared to pigs without PWD. The association between neutrophilic granulocyte infiltration in jejunum and PWD differed between the herds (P = 0.03). Furthermore, the associations between PWD and hyperleukocytosis (P = 0.04) or infiltration of eosinophilic granulocytes (P = 0.04) in ileum were also herd dependent. Histopathology revealed several lesions not relatable to PWD.
conclusionThe association between lesions and specific pathogens or PWD is more complex than anticipated.
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